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Record W4205715890 · doi:10.1111/tpj.15662

Untargeted metabolomic analyses reveal the diversity and plasticity of the specialized metabolome in seeds of different <i>Camelina sativa</i> genotypes

2022· article· en· W4205715890 on OpenAlexfundno aff
Stéphanie Boutet, Léa Barreda, François Perreau, Jean‐Chrisologue Totozafy, Caroline Mauve, Bertrand Gakière, Étienne Delannoy, Marie‐Laure Martin‐Magniette, Andrea Monti, Loı̈c Lepiniec, Federica Zanetti, Massimiliano Corso

Bibliographic record

VenueThe Plant Journal · 2022
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicLipid metabolism and biosynthesis
Canadian institutionsnot available
FundersAgriculture and Agri-Food CanadaInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'EnvironnementAgence Nationale de la Recherche
KeywordsCamelinaCamelina sativaMetabolomeBiologyMetabolomicsFlavonolsPhenotypic plasticitySiliqueCropFood scienceBotanyAgronomyBiochemistryArabidopsis thalianaAntioxidantFlavonoidGeneticsGeneBioinformatics

Abstract

fetched live from OpenAlex

SUMMARY Despite the essential role of specialized metabolites (SMs) in the interaction of plants with the environment, studying the ability of crop seeds to produce these protective compounds has been neglected. Furthermore, seeds produce a myriad of SMs, providing an interesting model to investigate their diversity and plasticity. Camelina sativa gained a lot of interest in the past few years as a rustic oilseed crop. A characterization of seed SM landscapes in six camelina genotypes grown in the field and harvested during five growing seasons has been undertaken in this work. This allowed a comprehensive annotation of seed SMs combining analyses that cluster SMs based on their chemical structures and co‐accumulation patterns. These data showed broad effects of the environment on the stimulation of the seed SM. Among well‐annotated compounds, flavonols were identified as the metabolic class characterized by high plasticity, revealing significant variable accumulation according to the year and/or the genotype. Lastly, a deeper characterization of primary metabolites and lipids in two selected genotypes has been performed. We showed that, in addition to flavonols, alkaloids and glucosinolates displayed a higher phenotypic plasticity with respect to most of the primary metabolites, including some sugars and major storage compounds such as fatty acids, proteins and most lipid classes (e.g. diacylglycerols, triacylglycerols), but similar plasticity compared with free amino acids and carboxylic acids. This work highlighted major and unexplored effects of the environment on the seed SM, demonstrating that seeds exhibit a dynamic and plastic metabolism, with an impact on seed quality.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.397
Threshold uncertainty score0.528

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.236
Teacher spread0.211 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations47
Published2022
Admission routes1
Has abstractyes

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