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Characterization of Photoproducts of <i>m</i>‐THPP in Aqueous Solution<sup>¶</sup>

2005· article· en· W4206004811 on OpenAlexaff
Natacha Lourette, Benoît Maunlt, Lina Bezdetnaya, Henri‐Pierre Lassalle, François Guillemin, Jean‐François Müller

Bibliographic record

VenuePhotochemistry and Photobiology · 2005
Typearticle
Languageen
FieldMedicine
TopicPhotodynamic Therapy Research Studies
Canadian institutionsCentre d'expertise et de recherche en infrastructures urbaines
Fundersnot available
KeywordsMass spectrometryChemistryTrimerPentamerTime-of-flight mass spectrometryIrradiationPorphyrinTetramerAqueous solutionDimerTandem mass spectrometryAnalytical Chemistry (journal)PhotochemistryNuclear chemistryIonizationChromatographyIonPhysical chemistryOrganic chemistry

Abstract

fetched live from OpenAlex

ABSTRACT This study examined the nature of photoproducts after pulse laser irradiation (647.5 nm) of 5,10,15,20‐tetrakis( meso ‐hydroxyphenyl)porphyrin ( m ‐THPP) (10 μmol/L) in ethanol‐water (1/99, vol/vol) solution. Spectroscopic measurements (UV‐visible absorption and fluorescence) and mass spectrometry techniques (matrix‐assisted laser desorption‐ionization [MALDI] coupled with time‐of‐flight mass spectrometer [TOF‐MS] or tandem time of flight mass spectrometer [TOF/TOF‐MS]) were used to follow photomodifications. Spectroscopic measurements evidenced photomodification as the main process after m ‐THPP irradiation. Three oxidized photoproducts at m/z 693.25, 695.24 and 713.25 were characterized by MS. After prolonged irradiation new isotopic distributions were registered at m/z 1355.41, 2031.57, 2707.80 and 3383.98 with MALDI‐TOF‐MS and TOF/TOF‐MS. These new photoproducts were attributed to covalent oligomeric structures as dimer, trimer, tetramer and pentamer of m ‐THPP.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.618

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.275
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2005
Admission routes1
Has abstractyes

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