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Most common concurrent infections with COVID-19

2022· article· en· W4206212200 on OpenAlexaff
Ahmed Ragab Zein, Emad A. Almuqati, Hebah H. Taher, Sarah S. Jahlan, Fatemah H. A. Khamis, Abdulwahab A Almansour, Shoroq Faisal Alhazmi, Maha M. Alshehri, Mohamed I. Obaidat, Muath A. Alshehri, Zahra H. Alhoori

Bibliographic record

VenueInternational Journal of Community Medicine and Public Health · 2022
Typearticle
Languageen
FieldImmunology and Microbiology
TopicAntibiotic Use and Resistance
Canadian institutionsASTER
Fundersnot available
KeywordsMedicinePseudomonas aeruginosaStaphylococcus aureusAntibioticsCoinfectionProspective cohort studyIntensive care medicineInternal medicineImmunologyMicrobiologyBiologyVirusBacteria

Abstract

fetched live from OpenAlex

Concurrent infections are a common complication of viral respiratory infections. They pose diagnostic challenges due to an overlap of similar symptoms, resistance to treatment and extending length of hospital stay. In this review we will extensively discuss the most common concurrent infections in patients with coronavirus disease 2019 (COVID-19). A thorough literature search was conducted in online databases such as PubMed, Google Scholar and included systematic reviews, meta-analyses, prospective and retrospective cohort studies in this review. Bacterial co-infections are the most common concurrent infections in patients with COVID-19 succeeded by viral and fungal co-infections. The prevalence of co-infections in COVID-19 patients is higher in intensive care units (ICU). Gram negative bacteria such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Escherichia coli, whereas gram positive bacteria such as Staphylococcus aureus are common pathogens for bacterial co-infections. The findings for the most common viral co-infection are inconsistent however, larger number of studies report respiratory viral co-infections such as influenza and respiratory syncytial virus. Fungal co-infections in COVID-19 patients are most commonly caused by the Candida spp. and occur predominantly in patients admitted in the ICU and are associated with high mortality and morbidity in COVID-19 patients. Continuous research on concurrent infections occurring in COVID-19 is essential. Larger prospective studies based on stratified groups of age, gender, and both ICU and non-ICU settings should be conducted. Studies on microbial susceptibility can lend more weight to empirical antibiotic and antifungal therapy. Early diagnosis of concurrent infections in COVID-19 is imperative to prevent poor patient outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.417
Threshold uncertainty score0.716

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.080
GPT teacher head0.383
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations1
Published2022
Admission routes1
Has abstractyes

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