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Record W4206371224 · doi:10.1017/cjn.2021.461

P.185 Impact-detecting helmets as indicators of concussion and blood brain barrier integrity in university football players

2021· article· en· W4206371224 on OpenAlexvenueno aff
Cheryl Jones, Lorelei Audas, Nelofar Kureshi, Lyna Kamintsky, Lynne Fenerty, Lindsay Wilson, Charles Atkinson, Alon Friedman, DB Clarke

Bibliographic record

VenueCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · 2021
Typearticle
Languageen
FieldMedicine
TopicTraumatic Brain Injury Research
Canadian institutionsnot available
Fundersnot available
KeywordsConcussionChronic traumatic encephalopathyMedicineFootballAthletesTraumatic brain injuryFootball playersPoison controlAmerican footballInjury preventionPhysical medicine and rehabilitationHead injuryPhysical therapyEmergency medicineSurgeryPsychiatry

Abstract

fetched live from OpenAlex

Background: Repetitive sub-concussive head impacts have been associated with changes in brain architecture and neurological symptoms. In this study, we examined the association between repetitive sub-concussive impacts, impact burden, and blood brain barrier (BBB) integrity in university football players. Methods: 59 university football players were followed over the 2019 season. Athletes with diagnosed concussion and those sustaining impacts that alerted a sideline impact monitor (relayed by ferroelectric helmet sensors) underwent dynamic contrast-enhanced MRI (DCE-MRI) within one week of injury/alert, and 4 weeks following initial incident. Results: Helmets recorded 2648 impacts over 48 cumulative hours. 8 concussions occurred during the 2019 season (2.82 per 1000 activity hours). On average, athletes with a diagnosed concussion had 55.3 impacts to the front sensor, compared to 14.1 in non-concussed athletes. Athletes who consented to DCE-MRI (n=5) had 10.78% BBB-D within a week of concussion/alert, and 6.77% BBB-D at 4-weeks. Conclusions: We show quantification of BBB integrity relative to head impact burden for the first time. This preliminary study highlights the potential of impact-detecting helmets to provide relevant impact characteristics and offers a foundation for future work on neurological consequences of repetitive sub-concussive impacts.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.025
Threshold uncertainty score0.050

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.320
Teacher spread0.274 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

Explore more

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