Correlation between Body Mass Index (BMI) and Performance on the Montreal Cognitive Assessment (MoCA) in a Cohort of Adult Women in South Africa
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Bibliographic record
Abstract
Objective. Recent evidence suggests that obesity is increasing worldwide and may negatively impact neurocognition. Local studies on the association of weight status with neurocognitive function are sparse. This study is aimed at examining the association between body mass index (BMI) and neurocognitive functioning scores in a cohort of adult women. Methods. A convenience sample of 175 women aged 18 to 59 years ( <a:math xmlns:a="http://www.w3.org/1998/Math/MathML" id="M1"> <a:mn>28.03</a:mn> <a:mo>±</a:mo> <a:mn>8.87</a:mn> </a:math> ) recruited in a community-based quantitative study completed the Montreal Cognitive Assessment (MoCA). The BMI metric was used to measure body fat based on weight and height and was stratified as high BMI (overweight or obese) or low BMI (normal weight). The Beck Depression Inventory (BDI) was used to assess depression. Pearson’s correlation analysis and the student’s <c:math xmlns:c="http://www.w3.org/1998/Math/MathML" id="M2"> <c:mi>t</c:mi> </c:math> -test analysis were performed. Results. We observed a significant inverse association between BMI and performance on MoCA ( <e:math xmlns:e="http://www.w3.org/1998/Math/MathML" id="M3"> <e:mi>r</e:mi> <e:mfenced open="(" close=")"> <e:mrow> <e:mn>173</e:mn> </e:mrow> </e:mfenced> <e:mo>=</e:mo> <e:mo>−</e:mo> <e:mn>0.32</e:mn> </e:math> , <i:math xmlns:i="http://www.w3.org/1998/Math/MathML" id="M4"> <i:mi>p</i:mi> <i:mo><</i:mo> <i:mn>0.001</i:mn> </i:math> ). Performance on subtest of attention, memory, constructive abstraction, and executive functions significantly and inversely correlated with BMI. Significantly lower scores on the MoCA were found in women with a high BMI compared to women with a low BMI ( <k:math xmlns:k="http://www.w3.org/1998/Math/MathML" id="M5"> <k:mn>23</k:mn> <k:mo>±</k:mo> <k:mn>4</k:mn> </k:math> vs. <m:math xmlns:m="http://www.w3.org/1998/Math/MathML" id="M6"> <m:mn>26</m:mn> <m:mo>±</m:mo> <m:mn>3</m:mn> </m:math> ), <o:math xmlns:o="http://www.w3.org/1998/Math/MathML" id="M7"> <o:mi>t</o:mi> <o:mfenced open="(" close=")"> <o:mrow> <o:mn>173</o:mn> </o:mrow> </o:mfenced> <o:mo>=</o:mo> <o:mn>4.12</o:mn> </o:math> , <s:math xmlns:s="http://www.w3.org/1998/Math/MathML" id="M8"> <s:mi>p</s:mi> <s:mo><</s:mo> <s:mn>0.0001</s:mn> </s:math> ). Conclusions. BMI and MoCA were inversely associated on both global and domain-specific neurocognitive test of attention, memory, and executive function; key neurocognitive control; and regulatory functions underlying behavior and decision-making. The findings provide a rationale for further research into the long-term effects of BMI on neurocognition.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it