Classifying antibiotics in the WHO Essential Medicines List for optimal use-be AWaRe
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Optimising the use of antimicrobials is a key priority of the global strategy to combat antimicrobial resistance. 1 WHOGlobal action plan on antimicrobial resistance. http://apps.who.int/iris/bitstream/10665/193736/1/9789241509763_eng.pdfDate: 2015 Google Scholar Antibiotic usage guidance should be developed to meet the aims of Sustainable Development Goal 3: achieving universal access to safe, effective, quality, and affordable medicines. 2 United NationsTransforming our world: the 2030 Agenda for Sustainable Development. https://sustainabledevelopment.un.org/content/documents/21252030%20Agenda%20for%20Sustainable%20Development%20web.pdfDate: 2015 Google Scholar Improving global prescribing is a complex issue that requires pragmatic short-term targets, ambitious long-term goals, and realistic expectations. In low-income and middle-income countries, it is difficult to identify specific targets for intervention. 3 Wirtz VJ Hogerzeil HV Gray AL et al. Essential medicines for universal health coverage. Lancet. 2017; 389: 403-476 Summary Full Text Full Text PDF PubMed Scopus (306) Google Scholar Furthermore, sustained, reliable availability of antibiotics at an affordable cost and adequate quality remains a major concern for high-income, low-income, and middle-income countries. 4 Pulcini C Beovic B Béraud G et al. Ensuring universal access to old antibiotics: a critical but neglected priority. Clin Microbiol Infect. 2017; 23: 590-592 Summary Full Text Full Text PDF PubMed Scopus (29) Google Scholar Regular shortages and the high cost of older, off-patent antibiotics are an increasing threat to their optimal use. 5 Pulcini C Mohrs S Beovic B et al. Forgotten antibiotics: a follow-up inventory study in Europe, the USA, Canada and Australia. Int J Antimicrob Agents. 2017; 49: 98-101 Crossref PubMed Scopus (30) Google Scholar Defining which antibiotics should be the focus at different levels of stewardship intervention is a global priority. 6 Davey P Marwick CA Scott CL et al. Interventions to improve antibiotic prescribing practices for hospital inpatients. Cochrane Database Syst Rev. 2017; 2 (CD003543) Crossref PubMed Scopus (301) Google Scholar
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it