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Record W4210462401 · doi:10.5376/mpb.2022.13.0003

Genetic Regulation of Fatty Acid Biosynthesis in <i>Brassica napus</i> Seeds Based on <i>FAE1</i> and <i>FAD2</i> Genes

2022· article· en· W4210462401 on OpenAlexvenueno aff
Chunxiu Lang, Fulin Wang, Renhu Liu, Tao Zheng, Zhanghua Hu, Xuelong Wu, WU Guan-ting

Bibliographic record

VenueMolecular Plant Breeding · 2022
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicLipid metabolism and biosynthesis
Canadian institutionsnot available
FundersNatural Science Foundation of Zhejiang Province
KeywordsErucic acidOleic acidBrassicaLinoleic acidBiochemistryFatty acidEnzymePolyunsaturated fatty acidFood scienceBiologyArabidopsisGeneChemistryBotanyMutant

Abstract

fetched live from OpenAlex

Fatty acid elongase 1 (FAE1) and delta-12 fatty acid desaturase 2 (FAD2) are two key enzymes in plant fatty acid biosynthesis pathway. Five different types of transgenic lines with identical genetic background were developed by single and double-expression regulation of the genes coding for these two key enzymes in the same  Brassica napus  variety CY2. Seeds of the five types of transgenic lines and the wild-type control, which were planted under the same environmental conditions, were analyzed and compared for fatty acid composition and oil content in the present study. The results showed that the contents of multiple fatty acids, such as oleic, linoleic, linolenic, eicosenoic and erucic acid, could be significantly altered by single and double regulation of the two genes. Particularly in the seeds in which the two endogenous target genes were simultaneously silenced, the oleic acid content was increased to 82.8% from 20.5% of CY2, and in the seeds with grain-specific expression of  Arabidopsis thaliana   FAE1  gene, the erucic acid content was raised to 60.2% from 43.9% of CY2. Compared with the wild-type control, the relative ratios of eighteen-carbon unsaturated fatty acids and the oleic desaturation proportion were all markedly changed in the five types of transgenic seeds. In addition, it was found that the seed oil content was improved by enhanced expression of  FAE1  and decreased by silencing of  FAE1  and  FAD2 , suggesting that the synthesis and accumulation of seed oil would be influenced to a certain extent by genetic manipulation of the two key enzyme genes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesMeta-epidemiology (narrow)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.175
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0010.002
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.201
Teacher spread0.191 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2022
Admission routes1
Has abstractyes

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