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Record W4210721220 · doi:10.1038/s41393-021-00744-z

The CanPain SCI clinical practice guidelines for rehabilitation management of neuropathic pain after spinal cord injury: 2021 update

2022· article· en· W4210721220 on OpenAlexafffundabout
Eldon Loh, Magdalena Mirkowski, Alexandria Roa Agudelo, David J. Allison, Brooke Benton, Thomas N. Bryce, Sara J. T. Guilcher, Tara Jeji, Anna Kras‐Dupuis, Denise Kreutzwiser, Oda Lanizi, Gary Lee-Tai-Fuy, James Middleton, Dwight E. Moulin, Colleen O’Connell, Steve Orenczuk, Patrick J. Potter, Christine Short, Robert Teasell, Andrea Townson, Eva Widerström-Noga, Dalton L. Wolfe, Nancy Xia, Swati Mehta

Bibliographic record

VenueSpinal Cord · 2022
Typearticle
Languageen
FieldMedicine
TopicSpinal Cord Injury Research
Canadian institutionsUniversity of British ColumbiaNova Scotia Health AuthorityStan Cassidy FoundationSciencetech (Canada)Ontario Neurotrauma FoundationDalhousie UniversityUniversity of TorontoSt Joseph's Health CareParkwood InstituteLawson Health Research InstituteWestern University
FundersOntario Neurotrauma Foundation
KeywordsMedicineNeuropathic painRehabilitationSpinal cord injuryGrading (engineering)Physical therapyClinical PracticeEvidence-based practiceMEDLINEEvidence-based medicineCritical appraisalGabapentinPhysical medicine and rehabilitationAlternative medicineSpinal cordPsychiatry

Abstract

fetched live from OpenAlex

STUDY DESIGN: Clinical practice guidelines. OBJECTIVES: The objective was to update the 2016 version of the Canadian clinical practice guidelines for the management of neuropathic pain in people with spinal cord injury (SCI). SETTING: The guidelines are relevant for inpatient, outpatient and community SCI rehabilitation settings in Canada. METHODS: The guidelines were updated in accordance with the Appraisal of Guidelines for Research and Evaluation II tool. A Steering Committee and Working Group reviewed the relevant evidence on neuropathic pain management (encompassing screening and diagnosis, treatment and models of care) after SCI. The quality of evidence was scored using Grading of Recommendations Assessment, Development and Evaluation (GRADE). A consensus process was followed to achieve agreement on recommendations and clinical considerations. RESULTS: The working group identified and reviewed 46 additional relevant articles published since the last version of the guidelines. The panel agreed on 3 new screening and diagnosis recommendations and 8 new treatment recommendations. Two key changes to these treatment recommendations included the introduction of general treatment principles and a new treatment recommendation classification system. No new recommendations to model of care were made. CONCLUSIONS: The CanPainSCI recommendations for the management of neuropathic pain after SCI should be used to inform practice.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.031
metaresearch head score (Gemma)0.022
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.753
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0310.022
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.152
GPT teacher head0.516
Teacher spread0.364 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations68
Published2022
Admission routes3
Has abstractyes

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