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Record W4210729913 · doi:10.1016/j.brs.2021.12.012

Toward focused ultrasound neuromodulation in deep brain stimulator implanted patients: Ex-vivo thermal, kinetic and targeting feasibility assessment

2022· letter· en· W4210729913 on OpenAlexaff
Can Sarica, Anton Fomenko, Jean‐François Nankoo, Ghazaleh Darmani, Artur Vetkas, Kazuaki Yamamoto, Andrés M. Lozano, Robert Chen

Bibliographic record

VenueBrain stimulation · 2022
Typeletter
Languageen
FieldEngineering
TopicUltrasound and Hyperthermia Applications
Canadian institutionsUniversity Health NetworkToronto Rehabilitation InstituteUniversity of Toronto
Fundersnot available
KeywordsNeuromodulationEx vivoUltrasoundMedicineFocused ultrasoundIn vivoBiomedical engineeringRadiologyInternal medicineStimulation

Abstract

fetched live from OpenAlex

Non-invasive transcranial ultrasound (TUS) neuromodulation is an emerging technique that has been demonstrated as safe in humans for cortical [1–5] and subcortical [6,7] targets. Deep brain stimulation (DBS) systems with local field potential (LFP) recording ability [8] might be utilized to record TUS-induced LFP changes and acoustic pressure induced artefact in the LFP recordings can be regarded as an evidence of engagement of acoustic waves with the target. Moreover, combining non-invasive brain stimulation with DBS has therapeutic implications, such as measuring alterations in pathological deep brain oscillations as an objective clinical outcome of TUS stimulation [9].

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.247
Teacher spread0.228 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations20
Published2022
Admission routes1
Has abstractyes

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