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Record W4210891427 · doi:10.7554/elife.73510.sa2

Author response: Impact of long- and short-range fibre depletion on the cognitive deficits of fronto-temporal dementia

2022· peer-review· en· W4210891427 on OpenAlexaff
Mélissa Savard, Tharick A. Pascoal, Stijn Servaes, Thijs Dhollander, Yasser Iturria‐Medina, Min Su Kang, Paolo Vitali, Joseph Therriault, Sulantha Mathotaarachchi, Andréa Lessa Benedet, Serge Gauthier, Pedro Rosa‐Neto

Bibliographic record

Venuenot available
Typepeer-review
Languageen
FieldNeuroscience
TopicNeurological Disease Mechanisms and Treatments
Canadian institutionsMontreal Neurological Institute and HospitalMcGill UniversityDouglas Mental Health University Institute
Fundersnot available
KeywordsFrontotemporal dementiaSemantic dementiaDementiaPsychologyCognitionAtrophyFrontotemporal lobar degenerationExecutive dysfunctionWhite matterDiseaseNeuroscienceNeuroimagingExecutive functionsSemantic memoryCognitive psychologyMedicinePathologyNeuropsychologyMagnetic resonance imagingRadiology

Abstract

fetched live from OpenAlex

While semantic symptoms in fronto-temporal dementia patients were mainly dependent on short-range white-matter fibre disruption, long-range white-matter fibres damage was the major contributor to executive dysfunction, highlighting the importance of controlling for risk factors associated with deep white-matter disease.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.078
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.120
Threshold uncertainty score0.402

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.078
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0020.002
Open science0.0010.002
Research integrity0.0070.005
Insufficient payload (model declined to judge)0.1200.053

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.107
GPT teacher head0.364
Teacher spread0.257 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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