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Record W4210958219 · doi:10.1002/9781118560273.ch8

Nucleophilic Aliphatic Substitution

2014· other· en· W4210958219 on OpenAlexaff
Kenneth Charles Westaway

Bibliographic record

VenueOrganic Reaction Mechanisms/Organic reaction mechanisms · 2014
Typeother
Languageen
FieldChemistry
TopicAsymmetric Synthesis and Catalysis
Canadian institutionsLaurentian University
Fundersnot available
KeywordsAllylic rearrangementSN2 reactionChemistryCatalysisSubstitution reactionNucleophilic substitutionNucleophilePropargylOrganic chemistrySN1 reactionMedicinal chemistry

Abstract

fetched live from OpenAlex

An allylic substitution has been accomplished by allowing two different substrate catalyst complexes to react together in a “dual catalytic” system. The reaction occurs after the allyl carbonate is converted into a substratepalladium metal catalyst complex and reacted with a vanadium metal–propargyl alcohol catalyst complex, giving the allylic substitution product. This chapter discusses four reviews on allylic substitution reactions. It also deals with reviews on oxirane ring-opening reactions. The chapter focuses on the use of ionic liquids in SN2 reactions. Density functional theory (DFT) calculations determine the rates of formation of aminofunctionalized ionic liquids in the SN2 reaction between various N-substituted imidazoles and 2-bromoethylamine. The chapter reviews the use of Brønsted acids, Lewis acids, metal complexes, and heteropoly acids as catalysts in the conversion of alcohols to carbenium ions in SN1 reactions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.032
Threshold uncertainty score0.106

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0320.011

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.210
Teacher spread0.202 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2014
Admission routes1
Has abstractyes

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Same venueOrganic Reaction Mechanisms/Organic reaction mechanismsSame topicAsymmetric Synthesis and CatalysisFrench-language works237,207