Iron Acquisition Strategies of Bacterial Pathogens
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Iron is essential to nearly all life forms on Earth, required for the proper function of enzymes involved in, for example, respiration, photosynthesis, the tricarboxylic acid cycle, nitrogen fixation, electron transport, and amino acid synthesis. The utility of iron in biological processes hinges on its chemical properties as a transition metal, engaging in single electron transfers to interconvert between the ferrous (Fe2+) and ferric (Fe3+) states. While this clearly makes iron advantageous, the same property provides the explanation for why excess, or “free”, iron is inherently toxic. Ferrous iron-catalyzed Fenton chemistry results in the generation of the highly toxic hydroxyl radical (OH•) that can compromise cellular integrity through damage to lipids, proteins, and nucleic acids.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it