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Record W4211258939 · doi:10.1016/j.kint.2019.02.022

Heart failure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

2019· article· en· W4211258939 on OpenAlexafffund
Andrew A. House, Christoph Wanner, Mark J. Sarnak, Ileana L. Piña, Christopher W. McIntyre, Paul Komenda, Bertram L. Kasiske, Anita Deswal, Christopher R. deFilippi, John G.F. Cleland, Stefan D. Anker, Charles A. Herzog, Michael Cheung, David C. Wheeler, Wolfgang C. Winkelmayer­, Peter A. McCullough, Ali K. Abu‐Alfa, Kerstin Amann, Kazutaka Aonuma, Lawrence J. Appel, Colin Baigent, George L. Bakris, Debasish Banerjee, John Boletis, Biykem Bozkurt, Javed Butler, Christopher T. Chan, Maria Rosa Costanzo, Ruth F. Dubin, Gerasimos Filippatos, Betty Muthoni Gikonyo, Dan Gikonyo, Roger J. Hajjar, Kunitoshi Iseki, Hideki Ishii, Greg Knoll, Colin R. Lenihan, Krista L. Lentine, Edgar V. Lerma, Etienne Macedo, Patrick B. Mark, Eisei Noiri, Alberto Palazzuoli, Roberto Pecoits‐Filho, Bertram Pitt, Claudio Rigatto, Patrick Rossignol, Soko Setoguchi, Manish M. Sood, Stefan Störk, Rita S. Suri, Karolina Szummer, Sydney Tang, Navdeep Tangri, Aliza Thompson, Krishnaswami Vijayaraghavan, Michael D. Walsh, Angela Yee‐Moon Wang

Bibliographic record

VenueKidney International · 2019
Typearticle
Languageen
FieldMedicine
TopicHeart Failure Treatment and Management
Canadian institutionsSeven Oaks General HospitalLondon Health Sciences CentreUniversity of ManitobaWestern University
FundersRelypsaCanadian Institutes of Health ResearchAbbott VascularNational Institutes of HealthAkebia TherapeuticsServierUniversity of OxfordSanofiKidney Foundation of CanadaBoston Scientific CorporationMyoKardiaFibroGenNational Heart, Lung, and Blood InstitutePfizerHeart and Stroke Foundation of CanadaUniversity of PittsburghAmgenAbbott DiagnosticsAstraZenecaEli Lilly and Company
KeywordsKidney diseaseDialysisMedicineHeart failureEjection fractionInternal medicineCardiologyHeart failure with preserved ejection fractionIntensive care medicine

Abstract

fetched live from OpenAlex

The incidence and prevalence of heart failure (HF) and chronic kidney disease (CKD) are increasing, and as such a better understanding of the interface between both conditions is imperative for developing optimal strategies for their detection, prevention, diagnosis, and management. To this end, Kidney Disease: Improving Global Outcomes (KDIGO) convened an international, multidisciplinary Controversies Conference titled Heart Failure in CKD . Breakout group discussions included (i) HF with preserved ejection fraction (HFpEF) and nondialysis CKD, (ii) HF with reduced ejection fraction (HFrEF) and nondialysis CKD, (iii) HFpEF and dialysis-dependent CKD, (iv) HFrEF and dialysis-dependent CKD, and (v) HF in kidney transplant patients. The questions that formed the basis of discussions are available on the KDIGO website http://kdigo.org/conferences/heart-failure-in-ckd/, and the deliberations from the conference are summarized here.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.055
metaresearch head score (Gemma)0.071
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.055
Threshold uncertainty score0.292

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0550.071
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.005
Bibliometrics0.0030.003
Science and technology studies0.0030.004
Scholarly communication0.0120.011
Open science0.0040.010
Research integrity0.0200.032
Insufficient payload (model declined to judge)0.0110.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.276
Teacher spread0.266 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations435
Published2019
Admission routes2
Has abstractyes

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