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Record W4212935265 · doi:10.21203/rs.3.rs-1351676/v1

Prenatal and postpartum maternal mental health and neonatal motor outcomes during the COVID-19 pandemic

2022· preprint· en· W4212935265 on OpenAlexafffund
Alissa Papadopoulos, Emily S. Nichols, Yalda Mohsenzadeh, Isabelle Giroux, Michelle F. Mottola, Ryan J. Van Lieshout, Emma G. Duerden

Bibliographic record

VenueResearch Square · 2022
Typepreprint
Languageen
FieldMedicine
TopicMaternal Mental Health During Pregnancy and Postpartum
Canadian institutionsMcMaster UniversityUniversity of OttawaWestern University
FundersCanada First Research Excellence Fund
KeywordsPregnancyEdinburgh Postnatal Depression ScaleMedicinePostpartum depressionDepression (economics)OffspringObstetricsPostpartum periodMental healthPrenatal careGross motor skillPerceived Stress ScaleBirth weightPediatricsMotor skillPsychiatryPopulationStress (linguistics)

Abstract

fetched live from OpenAlex

Abstract Background Rates of prenatal and postpartum stress and depression in pregnant individuals have increased during the COVID-19 pandemic. Perinatal maternal mental health has been linked to worse motor development in offspring, with motor deficits appearing in infancy and early childhood. We aimed to evaluate the relationship between prenatal and postpartum stress and depression and motor outcome in infants born during the COVID-19 pandemic. Methods One hundred and seventeen participants completed an online prospective survey study at two timepoints: during pregnancy and within 2 months postpartum. Depression was self-reported using the Edinburgh Perinatal/Postpartum Depression Scale (EPDS), and stress via the Perceived Stress Scale (PSS). Mothers reported total infant motor ability (fine and gross) using the interRAI 0–3 Developmental Domains questionnaire. Results Prenatal (B=-0.035, 95%CI=-0.062 to -0.007, p = .014) and postpartum maternal depression outcome (B=-0.037, 95%CI= -0.066 to -0.008, p = 0.012) were significant negative predictors of total infant motor ability (fine and gross). Neither pregnancy nor postpartum perceived stress predicted infant motor function. A cluster analysis revealed that preterm and low birth weight infants belonging to mothers who reported elevated depressive symptoms during pregnancy and in the postpartum period had the poorest motor outcome. Conclusions Prenatal and postpartum depression, but not stress, predicted infant motor ability during the first 2 months of life. Preterm and low-birth weight infants of mothers who report elevated depressive symptoms are the most at-risk of experiencing poor motor outcome.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies, Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.045
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.003
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.078
GPT teacher head0.429
Teacher spread0.351 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2022
Admission routes2
Has abstractyes

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