Instrumental activities of daily living in adults with the DM1 childhood phenotype: going beyond motor impairments
Bibliographic record
Abstract
Myotonic dystrophy type 1 (DM1) is the most common muscular dystrophy among adults. This cross-sectional study documents the level of independence in the instrumental activities of daily living (IADL) and explores the impact of executive functions and apathy on IADL accomplishment level among adults with the childhood phenotype of DM1. IADL accomplishment level was assessed with the Independent Living Scale (ILS) and the Activities of Daily Living Profile (ADL Profile). The later considered four operations related to executive functions: formulating a goal, planning, carrying out the task and goal attainment. Thirty-three individuals (19 females; mean age 39y, standard deviation 10y 6mo; range 23-57y) were recruited. According to the ILS total score, half of the participants were categorised as dependent. In financial management, no participant obtained the minimal score for independence. In the ADL Profile, higher dependence levels were frequent in IADL. Formulating a goal was the most difficult operation. Dependence level was more frequent in participants with apathy. Adults with the childhood phenotype exhibit significant difficulties in IADL accomplishment, especially considering their age. High levels of dependency observed with both outcome measures highlight their need for services to achieve optimal living conditions.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".