Basal ganglia stroke is associated with altered functional connectivity of the left inferior temporal gyrus
Bibliographic record
Abstract
BACKGROUND AND PURPOSE: Acute cerebral infarction in the basal ganglia is associated with an increased risk of cognitive impairment, suggesting that cognitive networks might be involved in neural plasticity after ischemic stroke. This study was conducted to explore the abnormalities in functional and causal connectivity of the brain network in patients with acute ischemic stroke (AIS) in the basal ganglia. METHODS: Resting-state functional magnetic resonance imaging was performed in 27 patients with AIS in the basal ganglia and 27 healthy controls (HCs). Brain regions with statistically different degree centrality (DC) values between groups were selected as seed points for granger causality analysis (GCA) analysis. The effective connectivity values of GCA were extracted, and the correlation between them and the Montreal Cognitive Assessment (MoCA) score was analyzed. RESULTS: Compared with HCs group, AIS patients displayed increased DC value in the left inferior temporal gyrus (ITG) and hippocampus head, reduced effective connectivity from the left ITG to the left precentral and postcentral gyri, increased effective connectivity from the left precentral and postcentral gyri to the left ITG, and reduced effective connectivity from the left anterior cingulate gyrus to the left ITG. The MoCA score of the AIS group was lower than that of the HCs group (t = -7.33, p < .05). CONCLUSION: Alterations of functional and causal connectivity among multiple brain regions suggest that patients with AIS in the basal ganglia have impairment of multifunctional networks in the whole brain.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".