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Validation of the Urticaria Control Test (UCT) in Children with Chronic Urticaria

2022· preprint· en· W4213123140 on OpenAlexaff
Connor Prosty, Sofianne Gabrielli, Pasquale Mulé, Nuzha Noorah, Sharon Baum, Shoshana Greenberger, Luís Felipe Ensina, Xun Zhang, Elena Netchiporouk, Moshe Ben‐Shoshan

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldMedicine
TopicUrticaria and Related Conditions
Canadian institutionsMcGill UniversityMcGill University Health Centre
FundersSanofi
KeywordsMedicineChronic urticariaCronbach's alphaInternal consistencyConvergent validityPediatricsInternal medicinePsychometricsClinical psychology

Abstract

fetched live from OpenAlex

ABSTRACT Background No validated tools exist to evaluate chronic urticaria (CU) control in children. While the Urticaria Control Test (UCT) exhibits favourable clinometric properties in adult CU, it is not yet validated in children. Therefore, we sought to evaluate the validity of the UCT for the assessment of pediatric CU. Methods Children presenting with CU were consecutively recruited. Participants completed both the UCT and the Children’s Dermatology Life Quality Index (CDLQI). We assessed the internal consistency, convergent and known-groups validity, and screening accuracy of the UCT at study entry and at follow-up. Results A total of 52 children with CU were recruited. The UCT exhibited respectable internal consistency in the evaluation of CU (Cronbach’s α=0.73 [95%CI: 0.62, 0.85]). UCT and CDLQI scores strongly correlated (r=-0.74, P<0.01). The UCT distinguished between different strata of disease severities established by the CDLQI (P<0.01). Screening accuracy of the UCT was excellent in the discrimination of poorly controlled CU (area under the curve=0.82). An optimal cut-off of ≤10 was determined for defining poorly controlled CU (sensitivity=95.5%, specificity=63.3%). Data at follow-up were consistent with data at study entry. Conclusion The UCT is a valid tool for the assessment of pediatric CU and CSU, as evidenced by acceptable internal consistency, convergent and known-groups validity, and screening accuracy at multiple time points.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.018
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.236
Teacher spread0.229 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2022
Admission routes1
Has abstractyes

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