MétaCan
Menu
Back to cohort

Chemical constituents from the leaves of Styrax argentifolius H.L. Li and their antioxidative activity

2021· article· en· W4213260645 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueDiscovery Phytomedicine - Journal of Natural Products Research and Ethnopharmacology · 2021
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicPlant-derived Lignans Synthesis and Bioactivity
Canadian institutionsnot available
FundersNational Foundation for Science and Technology Development
KeywordsLignanLupeolPhytochemicalChemistryDPPHSterolStereochemistryPinoresinolChemical constituentsTraditional medicineOrganic chemistryAntioxidantChromatographyBiochemistryCholesterol

Abstract

fetched live from OpenAlex

Searching for bioactive agents from medicinal plants, the phytochemical investigation on the EtOAc extract of the Vietnamese Styrax argentifolius leaves has resulted in the isolation and structural determination of five compounds, including one nor-neolignan egonoic acid (1), one lignan (+)-pinoresinol (2), one sterol (20R)-3β-hydroxysitgmasta-5,22-dien-7-one (3), and two triterpenoids lupeol (4), and 2α,3α,24-trihydroxy-urs-12-en-28-oic acid (5). The chemical structures of these secondary metabolites were elucidated by NMR and MS spectral data. All isolated compounds were first observed in S. argentifolius species. Sterol 3 and triterpenoid 5 were detected in genus Styrax for the first time. With the IC50 value of 19.10 µg/mL, compound 2 possessed the strong activity in DPPH radical scavenging assay.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.017
Threshold uncertainty score0.468

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.041
GPT teacher head0.338
Teacher spread0.297 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it