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Record W4213305094 · doi:10.1002/9783527626038.gloss

Glossary

2009· other· en· W4213305094 on OpenAlexfundno aff
Norbert Sewald, Prof. em. Dr. Hans-Dieter Jakubke

Bibliographic record

Venuenot available
Typeother
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicChemical Synthesis and Analysis
Canadian institutionsnot available
FundersCanadian Institute for Theoretical Astrophysics
KeywordsGlossaryLibrary scienceCitationPhilosophyComputer scienceLinguistics

Abstract

fetched live from OpenAlex

Ab amyloid-b.A 2 bu 2,4-diaminobutyric acid.aa amino acid.AA antamanide (anti-amanita peptide).Aad 2-aminoadipic acid.b-Aad 3-aminoadipic acid.AAP antimicrobial animal peptides.aatRS amino acyl tRNA synthetase.Ab antibody.ABPP activity-based protein profiling.ABP activity-based proteomics or activity-based probes.Abu a-aminobutyric acid.Abz aminobenzoic acid.Abzyme catalytic antibody, a monoclonal antibody with catalytic activity.Ac acetyl.ACE 2 angiotensin-converting enzyme 2. ACE angiotensin-converting enzyme.AChR acetylcholine receptor.Acm acetamidomethyl.ACP acyl carrier protein.ACTH corticotropin.Active pharmaceutical ingredients (API) a term for pharmaceutical market products considering peptides not only as hormones, as in the past, but as a major class of pharmaceutical products in antibiotics, antiviral and other therapeutic areas.AD Alzheimers disease.Ada adamantyl.ADME abbreviation of the pharmacological parameters absorption, delivery, metabolism, excretion.Adenohypophysis the anterior glandular lobe of the pituitary gland that constitutes of functional unit for the control of the secretion of many hormones, including ACTH, prolactin and growth hormone.Adoc adamantyloxycarbonyl. ADP adenosine diphosphate.Aet aminoethyl.Ag antigen.AGaloc tetra-O-acetyl-b-Dgalactopyranosyloxycarbonyl.AGE advanced glycation end products.AGloc tetra-O-acetyl-Dglucopyranosyloxycarbonyl.Agonist a ligand (e.g.hormone) of a receptor that elicits the same response as the native ligand.AGRP agouti-related protein.Ahx 2-aminohexanoic acid (norleucine).«-Ahx 6-aminohexanoic acid.AHZ b-alanyl-histidinato zinc.Aib a-aminoisobutyric acid.AIDS acquired immunodeficiency syndrome.Alanine scan systematic substitution of each amino acid residue of a native peptide by a simple amino acid such as alanine.A first step in structure-activity relationship studies.aIle allo-isoleucine (2S,3R in the L-series).Alzheimers disease (AD) the most prominent severe dementia in the elderly population, first described by Alzheimer in 1907.AD is a widespread, neurodegenerative, dementia-inducing disorder characterized mainly by amyloid deposits surrounding dying neurons (senile plaques), neurofibrillar degeneration with tangles, and cerebrovascular angiopathies.AD is clinically characterized by a progressive Peptides: Chemistry and Biology.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.640
Threshold uncertainty score0.000

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.008
Meta-epidemiology (narrow)0.0020.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0040.004
Science and technology studies0.0020.001
Scholarly communication0.0040.004
Open science0.0020.002
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.6400.562

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.003
GPT teacher head0.215
Teacher spread0.212 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2009
Admission routes1
Has abstractyes

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Same topicChemical Synthesis and AnalysisFrench-language works237,207