Prediction of Postoperative Speech Dysfunctions in Neurosurgery Based on Cortico-Cortical Evoked Potentials and Machine Learning Technology
Bibliographic record
Abstract
Intraoperative recording of cortico-cortical evoked potentials (CCEPs) enables studying effective connections between various functional areas of the cerebral cortex.The fundamental possibility of postoperative speech dysfunction prediction in neurosurgery based on CCEP signal variations could serve as a basis to develop the criteria for the physiological permissibility of intracerebral tumors removal for maximum preservation of the patients' quality of life.The aim of the study was to test the possibility of predicting postoperative speech disorders in patients with glial brain tumors by using the CCEP data recorded intraoperatively before the stage of tumor resection. Materials and Methods.CCEP data were reported for 26 patients.To predict the deterioration of speech functions in the postoperative period, we used four options for presenting CCEP data and several machine learning models: a random forest of decision trees, logistic regression, and support vector machine method with different types of kernels: linear, radial, and polynomial.Twenty variants of models were trained: each in 300 experiments with resampling.A total of 6000 tests were performed in the study. Results.The prediction quality metrics for each model trained in 300 tests with resampling were averaged to eliminate the influence of "successful" and "unsuccessful" data grouping.The best result with F1-score = 0.638 was obtained by the support vector machine with a polynomial kernel.In most tests, a high sensitivity score was observed, and in the best model, it reached a value of 0.993; the specificity of the best model was 0.370.Conclusion.This pilot study demonstrated the possibility of predicting speech dysfunctions based on CCEP data taken before the main stage of glial tumors resection; the data were processed using traditional machine learning methods.The best model with high sensitivity turned out to be insufficiently specific.Further studies will be aimed at assessing the changes in CCEP during the operation and their relationship with the development of postoperative speech deficit.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.007 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".