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Record W4220835134 · doi:10.1080/87559129.2022.2043895

Herbal Anxiolytics: Sources and Their Preparation Methods

2022· article· en· W4220835134 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueFood Reviews International · 2022
Typearticle
Languageen
FieldMedicine
TopicMedicinal Plant Extracts Effects
Canadian institutionsMcGill University
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsNutraceuticalContext (archaeology)AnxietyMedicineTraditional medicinePharmacologyPsychiatryBiology

Abstract

fetched live from OpenAlex

Anxiety is a disorder with known etiology and clinical symptoms which is managed by combination therapy or the use of complementary and alternative medicine (CAM), such as psychopharmacotherapy, cognitive behavioral therapy, and herbal medicine. The approach of scientists is to identify natural anxiolytics, based on their active components and their mechanism of action. So far, several medicinal plants have been identified and their effective components have been isolated and characterized as having cellular and molecular targets to the central nervous system (CNS). Despite the progress made in identification, application and drug interaction issues of such products, further studies should be planned to minimize their side effects and enhance their efficiency and specificity for a given health condition. The use of natural anxiolytics, either alone or in combination with other remedies can be improved by managing the preparation protocols, the route and the form of administration. In this context, natural drinks such as coffee with high levels of caffeine may exacerbate the clinical symptoms of anxiety. On the other hands, theanine (present in tea leaves) can alleviate the symptoms of the disorder. The current information available on traditional medicine and pharmacognosy is promising for formulation of nutraceuticals more specifically, with highest efficiency for prevention and treatment of anxiety. This review article attempts to introduce major herbs/plants recognized for their anti-anxiety effects and explain the feasibility for their specific application. The methods for the extract preparation and optimum condition for using such materials as traditional medicine or for their use in new formulations as nutraceuticals is suggested. The review also includes information about anxiety disorders, etiology, symptoms, types, neurobiology and different approaches to ameliorate anxiety conditions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.928
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.385
Teacher spread0.339 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it