The automatic localization of the vena contracta using Intracardiac Echocardiography (ICE): a feasibility study
Bibliographic record
Abstract
Recent recognition of the poor prognosis of significant tricuspid regurgitation (TR) has resulted in increased indication for tricuspid valve interventions. TR can affect 65% to 85% of the population worldwide and has a 1-year mortality rate greater than 25% in patients with severe regurgitation. A key procedure for patient selection and intraoperative assessment of intervention involves determining the location of the vena contracta width and regurgitant jet area. Manual visualization of the vena contracta (VC) can be time consuming depending on its location. Decreasing the required time for VC visualization would potentially result in decreased time for patient assessment, device deployment and intraprocedural intervention evaluation thus reducing hospital costs. There is currently no commercially available automatic VC detection system. We present a method to automatically localize the VC using 3D intracardiac echocardiography (ICE) on a simplified anthropomorphic phantom as a proof of concept. A beating heart phantom was outfitted with a silicone flange containing a mechanical valve and an orifice to cause a regurgitant jet. We propose an image processing pipeline to segment the regurgitant jet from Doppler ultrasound, as acquired by ICE, to determine the location of the VC automatically. The VC locations output by the algorithm were validated both qualitatively and quantitatively by comparison to manually annotated VC locations. On average, the location of VC detected by the algorithm was within 1.52±35mm to the location of the ground truth VC. We envision that this study will play a major role towards the development of an automated system for VC localization during TV interventions.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".