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Record W4220915926 · doi:10.1002/9781119794080.ch3

Specimen Collection

2022· other· en· W4220915926 on OpenAlexaff
William E. Schreiber

Bibliographic record

Venuenot available
Typeother
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicForensic Toxicology and Drug Analysis
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsDrugBlood collectionBlood testingMedicineBiomedical engineeringInternal medicineSurgeryPharmacologyEmergency medicine

Abstract

fetched live from OpenAlex

Testing for drugs and toxins can be performed on a variety of specimens. Choosing the most appropriate one depends on the purpose of the analysis. Blood is the specimen of choice for assessing the amount of active drug in a patient. Whole blood is required for certain analyses, because the drug or toxin of interest accumulates within red blood cells. This chapter discusses the issue of specimen validity testing. The window of detection is several hours to several days following drug use, depending on the specific drug and the amount and frequency of consumption. Many people are required to undergo drug testing as a condition of employment or to remain in drug rehabilitation programs. Specimen tampering can be divided into three categories: adulteration, substitution, and dilution. Dilute and substituted specimens are identified by comparing the values for creatinine and specific gravity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.010
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.098
Threshold uncertainty score0.327

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.010
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0050.002
Science and technology studies0.0030.001
Scholarly communication0.0030.002
Open science0.0030.003
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0980.093

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.069
GPT teacher head0.409
Teacher spread0.341 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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