Localized Statistical Shape Models for Large-Scale Problems With Few Training Data
Bibliographic record
Abstract
OBJECTIVE: Statistical shape models have been successfully used in numerous biomedical image analysis applications where prior shape information is helpful such as organ segmentation or data augmentation when training deep learning models. However, training such models requires large data sets, which are often not available and, hence, shape models frequently fail to represent local details of unseen shapes. This work introduces a kernel-based method to alleviate this problem via so-called model localization. It is specifically designed to be used in large-scale shape modeling scenarios like deep learning data augmentation and fits seamlessly into the classical shape modeling framework. METHOD: Relying on recent advances in multi-level shape model localization via distance-based covariance matrix manipulations and Grassmannian-based level fusion, this work proposes a novel and computationally efficient kernel-based localization technique. Moreover, a novel way to improve the specificity of such models via normalizing flow-based density estimation is presented. RESULTS: The method is evaluated on the publicly available JSRT/SCR chest X-ray and IXI brain data sets. The results confirm the effectiveness of the kernelized formulation and also highlight the models' improved specificity when utilizing the proposed density estimation method. CONCLUSION: This work shows that flexible and specific shape models from few training samples can be generated in a computationally efficient way by combining ideas from kernel theory and normalizing flows. SIGNIFICANCE: The proposed method together with its publicly available implementation allows to build shape models from few training samples directly usable for applications like data augmentation.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".