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Record W4221059655 · doi:10.15585/mmwr.mm7113a1

Universal Hepatitis B Vaccination in Adults Aged 19–59 Years: Updated Recommendations of the Advisory Committee on Immunization Practices — United States, 2022

2022· article· en· W4221059655 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

fundA Canadian funder is recorded on the work.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueMMWR Morbidity and Mortality Weekly Report · 2022
Typearticle
Languageen
FieldMedicine
TopicHepatitis B Virus Studies
Canadian institutionsnot available
FundersWake Forest School of MedicineHealth Resources and Services AdministrationCollege of Medicine, Drexel UniversityCenters for Disease Control and PreventionAmerican Pharmacists AssociationDrexel UniversityNationwide Children's HospitalMcMaster UniversityVanderbilt UniversityNational Center for HIV/AIDS, Viral Hepatitis, STD, and TB PreventionUniversity of WashingtonBrown UniversityStrongSaint Louis UniversityKaiser PermanenteResearch Institute, Nationwide Children's HospitalPediatric Infectious Diseases SocietyMinnesota Department of HealthGlaxoSmithKlineCouncil of State and Territorial EpidemiologistsNational Institutes of HealthAssociation for Prevention Teaching and ResearchU.S. Department of Health and Human Services
KeywordsMedicineAdvisory committeeVaccinationImmunizationImmunogenicityHepatitis BHepatitis A vaccineFamily medicineHepatitis B virusEnvironmental healthHepatitis B vaccineLimitingYoung adultPediatricsVirologyImmunologyGerontologyVirusAntibodyHBsAg

Abstract

fetched live from OpenAlex

Hepatitis B (HepB) vaccines have demonstrated safety, immunogenicity, and efficacy during the past 4 decades (1,2). However, vaccination coverage among adults has been suboptimal, limiting further reduction in hepatitis B virus (HBV) infections in the United States. This Advisory Committee on Immunization Practices (ACIP) recommendation expands the indicated age range for universal HepB vaccination to now include adults aged 19-59 years. Removing the risk factor assessment previously recommended to determine vaccine eligibility in this adult age group (2) could increase vaccination coverage and decrease hepatitis B cases.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.061
Threshold uncertainty score0.985

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.041
GPT teacher head0.317
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it