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The impact of perioperative stroke and delirium on outcomes after surgical aortic valve replacement
Steven R. Messé, Jessica Overbey, Vinod H. Thourani, Alan J. Moskowitz, Annetine C. Gelijns, Mark A. Groh, Michael J. Mack, Gorav Ailawadi, Karen L. Furie, Andrew M. Southerland, Michael L. James, Claudia S. Moy, Lopa Gupta, Pierre Voisine, Louis P. Perrault, Michael E. Bowdish, A. Marc Gillinov, Patrick T. O’Gara, Maral Ouzounian, Bryan A. Whitson, John C. Mullen, Marissa A. Miller, James S. Gammie, Stephanie Pan, Güray Erus, Jeffrey N. Browndyke, Wendy C. Taddei‐Peters, Neal Jeffries, Dennis Buxton, Nancy L. Geller, David Gordon, Catherine Burke, Albert Lee, Tyrone Smith, Ilana Kogan Gombos, Richard D. Weisel, Timothy J. Gardner, Eric A. Rose, Michael K. Parides, Deborah D. Ascheim, Emilia Bagiella, Ellen Moquete, Kinjal Shah, Helena Chang, Melissa Chase, Seth Goldfarb, Katherine Kirkwood, Edlira Dobrev, Ron Levitan, Karen O'Sullivan, Milerva Santos, Xia Ye, Rachelle Winkle, Haley Boswell, Amanda Fenlon, Melissa D. Johnson, Jessica Jones, Megan Kolb, Sarah Lam, L. F. Miranda, Jackie Ward, Renessa Whitman, Brittany Zingler, William H. Ryan, Robert L. Smith, Paul Grayburn, Pedro Nosnik, Eugene H. Blackstone, Nader Moazami, Randall C. Starling, Benico Barzilai, Richard A. Grimm, Edward G. Soltesz, Irene Katzan, Brian Strippy, Shoi Smith, Michelle Garcia, Mary Alice bowman, Carrie Geither, Robert Wang, Michael Argenziano, Michael A. Borger, Hiroo Takayama, Martin B. Leon, Lyn Goldsmith, Allan Schwartz, Nadia Sookraj, Talaya McCright‐Gill, S. Sreekanth, Jock N. McCullough, Alexander Iribarne, Joseph P. DeSimone, Anthony W. DiScipio, H. P. Stokes, Amanda St. Ivany, Gaylin Petty, Peter K. Smith, John H. Alexander, Carmelo A. Milano, Donald D. Glower, Joel Huber, Joel Morganlander, Joseph P. Mathew, Stacey Welsh, Sarah Casalinova, Victoria Johnson, Kathleen Lane, Derek Smith, Greg Tipton, Mark F. Berry, Judson B. Williams, Brian R. Englum, Matthew G. Hartwig, Robert Guyton, Omar M. Lattouf, Edward P. Chen, J. David Vega, Jefferson Baer, Duc Nguyen, Michael E. Halkos, Kim T. Baio, Tamara Prince, Natascha Cook, Alexis A. Neill, Mario Sénéchal, François Dagenais, Robert Laforce, Kim O’Connor, Gladys Dussault, Manon Caouette, Hugo Tremblay, Nathalie Gagné, Julie Dumont, Patricia Landry, Benjamin H. Trichon, Oliver A.R. Binns, Stephen Ely, Alan M. Johnson, Todd H. Hansen, John G. Short, Reid D. Taylor, Ralph Mangusan, Tracy Nanney, Holly Aubart, K. Simon Cross, Leslie McPeters, Christina Riggsbee, Lucy Rixey, Robert E. Michler, Joseph J. DeRose, Daniel J. Goldstein, Ricardo Bello, Cynthia C. Taub, Daniel M. Spevack, Kathryn Kirchoff, Rebecca Meli, Juan García, J.R. Goldenberg, Lauren Kealy, Louis P. Perrault, Denis Bouchard, Jean François Tanguay, Eileen O’Meara, Jonathan Lacharité, Sophie Robichaud, Keith A. Horvath, Philip C. Corcoran, Michael Siegenthaler, Mandy Murphy, Margaret Iraola, Ann Greenberg, Greg Kumkumian, Mark R. Milner, Zurab Nadareishvili, Ayesha Hasan, Asia McDavid, Denise Fadorsen, Terry Yau, Michael E. Farkouh, Anna Woo, Robert J. Cusimano, Tirone E. David, Christopher M. Feindel, Nishit Fumakia, Shakira Christie, Asvina Bissonauth, Alexandra Hripko, Zahid Noor, Kristen M. Mackowick, Stephanie Deasey, Manal Al-Suqi, Julia Collins, Michael A. Acker, James N. Kirkpatrick, Mary Lou Mayer, Caitlin McDonald, Holley Fok, Breanna Maffei, Stephen Cresse, Christine Gepty, Vaughn A. Starnes, David Shavalle, Christi Heck, Amy Hackmann, Craig Baker, Fernando Fleischman, Mark J. Cunningham, Edward Lozano, Michelle L. Hernandez, Irving L. Kron, Karen C. Johnston, Ravi K. Ghanta, John Dent, John A. Kern, Leora T. Yarboro, Michael Ragosta, Brian H. Annex, J.A. Bergin, Sandra G. Burks, Mike Cosner, China Green, Samantha Loya, Hye Ryun Kim, David A. Bull, Patrice Desvigne‐Nickens, Dennis O. Dixon, Rebecca F. Gottesman, Mark C. Haigney, Richard Holubkov, Alice Jacobs, Eric M. Meslin, John M. Murkin, John A. Spertus, Frank W. Sellke, Cheryl L. McDonald, John M. Canty, Neal W. Dickert, John S. Ikonomidis, KyungMann Kim, David O. Williams, Clyde W. Yancy, Seemant Chaturvedi, Marc I. Chimowitz, James C. Fang, Wayne Richenbacher, Vivek Rao, Rachel Miller, Jennifer Cook, David A. D’Alessandro, Frederick T. Han, Sean Pinney, Mary Norine Walsh, David M. Greer, Koto Ishida, Christian Stapf, Judy Hung, Xin Zeng, David Hung, Sudarat Satitthummanid, Michel Billelo, Christos Davatzikos, Lauren Karpf, Lisa Desiderio, Yanne Toulgoat-Dubois, R. Brassard, Renu Virmanu, Maria Romero, Ryan Braumann
Bibliographic record
VenueJournal of Thoracic and Cardiovascular Surgery · 2022
Typearticle
Languageen
FieldMedicine
TopicIntensive Care Unit Cognitive Disorders
Canadian institutionsUniversity of AlbertaToronto General HospitalMontreal Heart InstituteInstitut universitaire de cardiologie et de pneumologie de Québec
FundersNational Institute of Neurological Disorders and StrokeNational Heart, Lung, and Blood InstituteCanadian Institutes of Health ResearchNational Institutes of Health
KeywordsMedicineDeliriumStroke (engine)Hazard ratioPerioperativeOdds ratioInternal medicineAortic valve replacementConfidence intervalNeurocognitiveCardiologyAnesthesiaIntensive care medicineCognitionStenosisPsychiatry
Abstract
No abstract in any covered source. Its absence is recorded, not treated as a negative.
No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.127
Threshold uncertainty score0.391
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.002 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
Opus teacher head0.014
GPT teacher head0.306
Teacher spread0.292 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".
Quick stats
Citations11
Published2022
Admission routes2
Has abstractno