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Record W4224000475 · doi:10.3233/npm-229003

Proceedings of the 13th International Newborn Brain Conference: Neuroprotection strategies in the neonate

2022· article· en· W4224000475 on OpenAlexaff
Ayman Abou Mehrem, Essa Al Awad, Kim Anninck, Stephanie H. Au‐Young, Nesil Aydinol, Peter Bartmann, Manon J.N.L. Benders, Amina Benlamri, Leah Bolderheij, Yalçın Çelik, Natalie Pui Ha Chan, Cecil M. Y. Chau, Vann Chau, Xiaodi Chen, Claudia Chetcuti Ganado, Annaleen Coetser, Filip Cools, Giselle Da Rocha, Hans‐Peter Deigner, A Dereymaeker, Laxmikant Deshmukh, Rose Domonoske, Salma Dossani, Jeanne Maria Dsouza, Mayy El Gamal, Peace Eshemokhai, Michael J. Esser, Elsa Fiedrich, Axel R. Franz, Anirban Ghosh, Floris Groenendaal, Ruth E. Grunau, Sujith Kumar Reddy Gurram Venkata, Serif Hamitoğlu, Lena Hellström‐Westas, Leigh Irvine, Katrien Jansen, Artem Javadyan, Graham Jenkin, Noela Kamanga, Navneet Kaur, Elif Keleş, Matthias Keller, Edmond Kelly, Samantha Jane Kesting, Dikeledi Maureen Kgwadi, Bo-Ram Kim, Matthias Kohl, Derek Kowal, Jennifer Damoi Kricitober, Lara M. Leijser, Mark LePine, Yow‐Pin Lim, Abhay Lodha, Atul Londhe, Linh Ly, Eva Maes, Atul Malhotra, Neil Marlow, Joseph L. Mathew, Courtney McDonald, Mia A. McLean, Cathy Metcalfe, Ron Meyer, Steven P. Miller, Stephanie Miller, Tshiamo Mogajane, Khorshid Mohammad, Sarfaraz Momin, John Montpetit, Nelson Mukiza, Prashanth Murthy, James N. Scott, Victoria Nakibuuka, Firdose Nakwa, Gunnar Naulaers, Jennessa Noort, Nandi Ntuli, Claude Ondongo-Ezhet, Renee Paul, Michael S. Pepper, Achim Plum, Bryan Rombough, Ola Didrik Saugstad, Jillian Scotland, J. F. Scott, Karabo Seake, Robert Sebunya, Thiviya Selvanathan, Letlhogonolo Sepeng, Hüseyin Şimşek, Carola Steins-Rang, Barbara S. Stonestreet, Selphee Tang, Erdal Taşkın, Liesbeth Thewissen, Sumesh Thomas, Reenu Thomas, Alison van Kwawegen, Jeanne Van Rensburg, Sithembiso Velaphi, Yuqi Wu, Akan Yaman, Hacer Yapıcıoğlu-Yıldızdaş, Tamara Yawno, Pearl Zaki, Hussein Zein, Lindsay Zhou

Bibliographic record

VenueJournal of Neonatal-Perinatal Medicine · 2022
Typearticle
Languageen
FieldNeuroscience
TopicAnesthesia and Neurotoxicity Research
Canadian institutionsHospital for Sick ChildrenBC Children's HospitalUniversity of TorontoSickKids FoundationMount Sinai Hospital
Fundersnot available
KeywordsNeuroprotectionNeuroscienceCognitive scienceMedicinePsychology

Abstract

fetched live from OpenAlex

BACKGROUND: Hypoxic-ischemic (HI) brain injury is one of the most common neurological problems observed in infants. Hypothermia is the only approved therapy for neonatal HI encephalopathy. This therapy is only partially protective, cannot be used in preterm infants, and has a narrow therapeutic window after birth. Therefore, additional adjunctive therapies are urgently required. IAIPs are naturally plasma-derived proteins. We have previously shown that IAIP alone reduces cortical neuronal cell death, improves behavior outcomes, and attenuates brain volume loss in neonatal HI rats (

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.725
Threshold uncertainty score0.535

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0020.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.303
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

Explore more

Same venueJournal of Neonatal-Perinatal MedicineSame topicAnesthesia and Neurotoxicity ResearchFrench-language works237,207