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Record W4224319035 · doi:10.21203/rs.3.rs-1581727/v1

SARS-CoV-2 infection in technology dependent children: a multicenter case series

2022· preprint· en· W4224319035 on OpenAlexaffabout
Joan Robinson, Tammie Dewan, Shaun K. Morris, Ari Bitnun, Peter J. Gill, Tala El Tal, Ronald M. Laxer, E. Ann Yeh, Carmen Yea, Rolando Ulloa‐Gutiérrez, Helena Brenes-Chacón, Adriana Yock‐Corrales, Gabriela Ivankovich‐Escoto, Alejandra Soriano‐Fallas, Marcela Hernández-de Mezerville, Jesse Papenburg, Marie‐Astrid Lefebvre, Alireza Nateghian, Behzad Haghighi, Ali Anari Manafi, Rachel Dwilow, Jared Bullard, Suzette Cooke, Léa Restivo, Alison Lopez, Manish Sandarangani, Ashley Roberts, Nicole LeSaux, Jennifer Bowes, Rupeena Purewal, Janell Lautermilch, Jacqueline Wong, Dominique Piché, Karina A. Top, Cheryl Foo, Luc Panetta, Joanna Merckx, Michelle Barton

Bibliographic record

VenueResearch Square · 2022
Typepreprint
Languageen
FieldPsychology
TopicCOVID-19 and Mental Health
Canadian institutionsMemorial University of NewfoundlandMcMaster UniversityMcGill UniversityUniversity of OttawaUniversity of British ColumbiaUniversity of ManitobaUniversity of CalgaryDalhousie UniversityWestern UniversityUniversity of TorontoUniversité de MontréalUniversity of SaskatchewanUniversity of Alberta
Fundersnot available
KeywordsMedicineDemographicsMechanical ventilationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PediatricsCoronavirus disease 2019 (COVID-19)Stage (stratigraphy)Ventilation (architecture)Emergency medicineAnesthesiaInternal medicineDemographyDisease

Abstract

fetched live from OpenAlex

Abstract Purpose: The objective of this study was to describe the clinical course and outcomes in children with technology-dependence (TD) hospitalized with SARS-CoV-2 infection.Methods: Seventeen pediatric hospitals (15 Canadian and one each in Iran and Costa Rica) included children up to 17 years of age admitted February 1, 2020, through May 31, 2021, with detection of SARS-CoV-2. For those with TD, data were collected on demographics, clinical course and outcome. Results: Of 691 children entered in the database, 42 (6%) had TD of which 22 had feeding tube dependence only, 9 were on supplemental oxygen only, 3 had feeding tube dependence and were on supplemental oxygen, 2 had a tracheostomy but were not ventilated, 4 were on non-invasive ventilation, and 2 were on mechanical ventilation prior to admission. Three of 42 had incidental SARS-CoV-2 infection. Two with end-stage underlying conditions were transitioned to comfort care and died. Sixteen (43%) of the remaining 37 cases required increased respiratory support from baseline due to COVID-19 while 21 (57%) did not. All survivors were discharged home.Conclusion: Children with TD appear to have an increased risk of COVID-19 hospitalization. However, in the absence of end-stage chronic conditions, all survived to discharge.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.128
GPT teacher head0.517
Teacher spread0.389 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes2
Has abstractyes

Explore more

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