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Record W4224718928 · doi:10.1002/sim.9417

Variable selection in semiparametric regression models for longitudinal data with informative observation times

2022· article· en· W4224718928 on OpenAlexafffund
Omidali Aghababaei Jazi, Eleanor Pullenayegum

Bibliographic record

VenueStatistics in Medicine · 2022
Typearticle
Languageen
FieldMathematics
TopicStatistical Methods and Inference
Canadian institutionsInstitute for Clinical Evaluative SciencesSickKids FoundationHospital for Sick ChildrenUniversity of Toronto
FundersCanadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada
KeywordsSemiparametric regressionCovariateEstimatorRegressionSemiparametric modelRegression analysisStatisticsFeature selectionEconometricsOutcome (game theory)Flexibility (engineering)Computer scienceMathematicsArtificial intelligence

Abstract

fetched live from OpenAlex

A common issue in longitudinal studies is that subjects' visits are irregular and may depend on observed outcome values which is known as longitudinal data with informative observation times (follow-up). Semiparametric regression modeling for this type of data has received much attention as it provides more flexibility in studying the association between regression factors and a longitudinal outcome. An important problem here is how to select relevant variables and estimate their coefficients in semiparametric regression models when the number of covariates at baseline is large. The current penalization procedures in semiparametric regression models for longitudinal data do not account for informative observation times. We propose a variable selection procedure that is suitable for the estimation methods based on pseudo-score functions. We investigate the asymptotic properties of penalized estimators and conduct simulation studies to illustrate the theoretical results. We also use the procedure for variable selection in semiparametric regression models for the STAR*D dataset from a multistage randomized clinical trial for treating major depressive disorder.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.035
metaresearch head score (Gemma)0.102
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.035
Threshold uncertainty score0.187

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0350.102
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.003
Bibliometrics0.0020.003
Science and technology studies0.0010.003
Scholarly communication0.0020.003
Open science0.0030.003
Research integrity0.0020.004
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.205
GPT teacher head0.430
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2022
Admission routes2
Has abstractyes

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