Insights into the effects of vibration on skeletal development and growth in teleosts
Bibliographic record
Abstract
Teleosts are superb models to study development and growth because their entire life history can be studied in a laboratory setting. The objective of this research is to understand the impacts of the external environment, namely whole body low frequency vibrations on skeletal development. We exposed zebrafish larvae at different stages of development to low frequency vibrations by placing them on a custom built vibration instrument for four days. Our results show age‐related and bone‐type specific effects. For example, some cartilages of the caudal fin were affected while others were not. This data suggests that chondrogenic cell progenitors are capable of sensing and reacting to mechanical stimuli early during development. Furthermore, we show that this effect is sox9‐independent. In summary, this data shows that there is a critical window during early caudal fin development that is susceptible to environmental influence. The plasticity of the skeleton to respond to and adapt to external influence is remarkable. These responses often have lasting impacts on the resulting phenotype and provides a hint at how development influences evolution.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".