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Record W4225419614 · doi:10.1038/s41467-022-30009-z

Palaeogenomic analysis of black rat (Rattus rattus) reveals multiple European introductions associated with human economic history

2022· article· en· W4225419614 on OpenAlexaff
Yu He, Alexandra Jamieson, Ardern Hulme‐Beaman, Chris J. Conroy, Becky Knight, Camilla Speller, Hiba Al-Jarah, Heidi Eager, Alexandra Trinks, G. Adikari, Henriette Baron, Beate Böhlendorf‐Arslan, Wijerathne Bohingamuwa, Alison Crowther, Thomas Cucchi, Kinie Esser, Jeffrey Fleisher, Louisa Gidney, Elena Gladilina, Pavel Gol’din, Steven M. Goodman, Sheila Hamilton‐Dyer, Richard Helm, Jesse C. Hillman, Nabil Kallala, Hanna Kivikero, Zsófia Eszter Kovács, Günther Karl Kunst, René Kyselý, Anna Linderholm, Bouthéina Maraoui-Telmini, Nemanja Marković, Arturo Morales Muñiz, Mariana Nabais, Terry O’Connor, Tarek Oueslati, Eréndira M. Quintana Morales, Kerstin Pasda, Jude Perera, Nimal Perera, Silvia Radbauer, Joan Ramon, Eve Rannamäe, Joan Sanmartí Grego, Edward R. Treasure, Sílvia Valenzuela, Inge van der Jagt, Wim Van Neer, Jean‐Denis Vigne, Thomas Walker, Stephanie Wynne‐Jones, Jørn T. Zeiler, Keith Dobney, Nicole Boivin, Jeremy B. Searle, Ben Krause‐Kyora, Johannes Krause, Greger Larson, David Orton

Bibliographic record

VenueNature Communications · 2022
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicYersinia bacterium, plague, ectoparasites research
Canadian institutionsSimon Fraser UniversityUniversity of British Columbia
FundersArts and Humanities Research CouncilMax-Planck-Institut für MenschheitsgeschichteHenan Institute of Science and TechnologyNatural Environment Research CouncilAkademie Věd České RepublikyMax-Planck-GesellschaftUniversity of OxfordEesti TeadusagentuurMax-Planck-Institut für Evolutionäre AnthropologieLeverhulme TrustBritish AcademyUniversitat de BarcelonaMinisterio de Ciencia e InnovaciónWellcome TrustNational Science Foundation
KeywordsBiological dispersalAncient DNAPlague (disease)PopulationDemographic historyRodentBiologyMediterranean climateGeographyZoologyEvolutionary biologyEcologyGenetic diversityDemographyArchaeology

Abstract

fetched live from OpenAlex

The distribution of the black rat (Rattus rattus) has been heavily influenced by its association with humans. The dispersal history of this non-native commensal rodent across Europe, however, remains poorly understood, and different introductions may have occurred during the Roman and medieval periods. Here, in order to reconstruct the population history of European black rats, we first generate a de novo genome assembly of the black rat. We then sequence 67 ancient and three modern black rat mitogenomes, and 36 ancient and three modern nuclear genomes from archaeological sites spanning the 1st-17th centuries CE in Europe and North Africa. Analyses of our newly reported sequences, together with published mitochondrial DNA sequences, confirm that black rats were introduced into the Mediterranean and Europe from Southwest Asia. Genomic analyses of the ancient rats reveal a population turnover in temperate Europe between the 6th and 10th centuries CE, coincident with an archaeologically attested decline in the black rat population. The near disappearance and re-emergence of black rats in Europe may have been the result of the breakdown of the Roman Empire, the First Plague Pandemic, and/or post-Roman climatic cooling.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.284
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations54
Published2022
Admission routes1
Has abstractyes

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Same venueNature CommunicationsSame topicYersinia bacterium, plague, ectoparasites researchFrench-language works237,207