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Record W4225613048 · doi:10.21203/rs.3.rs-1507728/v1

Frequency and predictors of post-stroke cognitive impairment in Ethiopian stroke survivors: A cross-sectional study

2022· preprint· en· W4225613048 on OpenAlexaboutno aff
Yared Z. Zewde, Atalay Alem, Susanne Seeger

Bibliographic record

VenueResearch Square · 2022
Typepreprint
Languageen
FieldMedicine
TopicStroke Rehabilitation and Recovery
Canadian institutionsnot available
FundersFogarty International CenterNational Institutes of Health
KeywordsStroke (engine)CognitionDementiaMedicineMontreal Cognitive AssessmentCross-sectional studyModified Rankin ScaleDepression (economics)Physical therapyCognitive declineGerontologyCognitive impairmentPsychiatryInternal medicineIschemic strokeDisease

Abstract

fetched live from OpenAlex

Abstract Background: Stroke is emerging as a public health threat to sub-Saharan African countries. Even though cognitive impairment is increasingly being recognized as a major cause of disability in stroke survivors there is no data on the burden of stroke related cognitive dysfunction from Ethiopia. In this study, we aimed to assess the frequency and predictors of post-stroke cognitive impairment in Ethiopian stroke survivors.Methods: Participants were adult stroke survivors who came for follow-up at least 3 months after the last stoke. Demographic and clinical data were collected using a structured questionnaire. We employed the Montreal Cognitive Assessment Scale-Basic (MOCA-B), modified Rankin Scale (mRS) and Patient Health Questionnaire-9 (PHQ-9) to assess post-stroke cognition, functional recovery, and depression, respectively.Results: Among 67 stroke survivors (mean age: 52.1 ± 12.7 years, females: 40.3%, low or no education: 41.8%, median stroke duration: 3 years), 28 (41.8%) had post-stroke cognitive impairment. Of these, 20 (30%) had mild cognitive impairment and 8 (12%) had post-stroke dementia. On multivariate analysis, increased age [AOR=0.24, 95% CI (0.07,0.83)], lower education [AOR=4.02, 95% CI (1.13,14.32)] and poor function recovery (mRS ³3) [AOR=0.27, 95% CI (0.08-0.81)] were independently associated with post-stroke cognitive impairment.Conclusion:Cognitive impairment is frequent among Ethiopian stroke survivors. We found that increased age, low educational attainment, and poor recovery on physical function were independently associated with cognitive decline. Although causality cannot be inferred, physical rehabilitation and better education might play a significant role in building cognitive resilience among stroke survivors.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.049
GPT teacher head0.413
Teacher spread0.365 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2022
Admission routes1
Has abstractyes

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