Corrigendum to “Decreases in Suicidality Following Psychedelic Therapy
Bibliographic record
Abstract
To the Editor: Our group recently published in JCP the first meta-analysis of patient-level data on the effects of psychedelics on suicidality. 1 While not described in our article, it is noteworthy that 2 suicidality-related events that had been deemed not attributable to the administration of a psychedelic (by the authors of the primary outcome studies) occurred within the studies included in our meta-analysis.Griffiths et al 2 describe in their supplementary materials that 1 individual in their very low-dose (placebo-like) psilocybin condition completed suicide 11 days after being administered 1 mg/70 kg psilocybin.The individual reported feeling bored during the session and was discontinued from the study after leaving the session early.They also report that there was no behavioral impairment or adverse sequelae during the follow-up later that day or on subsequent days.Andersen et al 3 report that 1 individual attempted suicide approximately 2 months after being administered an active dose of psilocybin (21-25.2mg/70 kg).The suicide attempt occurred after the individual learned about the sudden death of a former partner, subsequently used methamphetamine and crack cocaine, and then experienced a brief psychotic episode.They reported that the actual lethality of the attempt was 0 and the potential lethality was a 2 on the Columbia Suicide Severity Rating Scale.Although these events are likely not attributable to psychedelic therapy itself, they are nonetheless worthy of consideration and suggest the importance of closely monitoring patients in all treatment arms throughout and following psychedelic therapy trials.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.013 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.002 | 0.002 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.003 | 0.000 |
| Research integrity | 0.001 | 0.006 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".