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Record W4229449868 · doi:10.1007/s12028-022-01505-3

Proceedings of the Second Curing Coma Campaign NIH Symposium: Challenging the Future of Research for Coma and Disorders of Consciousness

2022· article· en· W4229449868 on OpenAlexaff
Shraddha Mainali, Venkatesh Aiyagari, Sheila Alexander, Yelena G. Bodien, Varina L. Boerwinkle, Mélanie Boly, Emery N. Brown, Jeremy Brown, Jan Claassen, Brian L. Edlow, Ericka L. Fink, Joseph J. Fins, Brandon Foreman, Jennifer Frontera, Romergryko G. Geocadin, Joseph T. Giacino, Emily J. Gilmore, Olivia Gosseries, Flora M. Hammond, Raimund Helbok, J. Claude Hemphill, Karen G. Hirsch, Keri S. Kim, Steven Laureys, Ariane Lewis, Geoffrey Ling, Sarah Livesay, Victoria McCredie, Molly McNett, David Menon, Erika Molteni, DaiWai M. Olson, Kristine O’Phelan, Soojin Park, Len Polizzotto, J. Javier Provencio, Louis Puybasset, Chethan P. Venkatasubba Rao, Courtney Robertson, Benjamin Rohaut, Michael Rubin, Tarek Sharshar, Lori Shutter, Gisele Sampaio Silva, Wade S. Smith, Robert D. Stevens, Aurore Thibaut, Paul Vespa, Amy K. Wagner, Wendy Ziai, Elizabeth Zink, José I. Suarez

Bibliographic record

VenueNeurocritical Care · 2022
Typearticle
Languageen
FieldMedicine
TopicTraumatic Brain Injury Research
Canadian institutionsUniversity of Toronto
FundersNational Center for Advancing Translational SciencesNational Institute of Neurological Disorders and StrokeNational Institutes of HealthNeurocritical Care Society
KeywordsComa (optics)DeliverableConsciousnessMedicinePersistent vegetative stateEngineering ethicsMinimally conscious stateMedical educationPsychologyNeuroscienceEngineering

Abstract

fetched live from OpenAlex

This proceedings article presents actionable research targets on the basis of the presentations and discussions at the 2nd Curing Coma National Institutes of Health (NIH) symposium held from May 3 to May 5, 2021. Here, we summarize the background, research priorities, panel discussions, and deliverables discussed during the symposium across six major domains related to disorders of consciousness. The six domains include (1) Biology of Coma, (2) Coma Database, (3) Neuroprognostication, (4) Care of Comatose Patients, (5) Early Clinical Trials, and (6) Long-term Recovery. Following the 1st Curing Coma NIH virtual symposium held on September 9 to September 10, 2020, six workgroups, each consisting of field experts in respective domains, were formed and tasked with identifying gaps and developing key priorities and deliverables to advance the mission of the Curing Coma Campaign. The highly interactive and inspiring presentations and panel discussions during the 3-day virtual NIH symposium identified several action items for the Curing Coma Campaign mission, which we summarize in this article.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.656
Threshold uncertainty score0.327

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.351
Teacher spread0.309 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations47
Published2022
Admission routes1
Has abstractyes

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