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Case Report: A castration-resistant terminal prostate cancer patient’s survival prolonged after practicing Falun Gong

2020· preprint· en· W4229553565 on OpenAlexaff
Yuhong Dong, Shawn Wu, Ann Corson, Kai-Hsiung Hsu

Bibliographic record

VenueF1000Research · 2020
Typepreprint
Languageen
FieldMedicine
TopicProstate Cancer Treatment and Research
Canadian institutionsHealth Sciences CentreSunnybrook Health Science Centre
Fundersnot available
KeywordsMedicineProstate cancerCastrationAndrogen deprivation therapyInternal medicineCancerOncologyUrologyHormone

Abstract

fetched live from OpenAlex

<ns3:p><ns3:bold>Background:</ns3:bold> Most metastatic prostate cancer patients receive combined androgen blockade (CAB) as the mainstay of treatment. Unfortunately, patients ultimately progress to castration resistance.</ns3:p><ns3:p> <ns3:bold>Clinical finding and diagnosis: </ns3:bold>We describe a man in his eighties who developed stage IV, M1b prostate cancer, multiple (≥5) bone metastases, and required the aid of a walker to ambulate. Without treatment, his treating physician predicted he would survive 6 months.</ns3:p><ns3:p> <ns3:bold>Interventions and outcomes:</ns3:bold> The patient initially responded well to treatment with CAB, but during the 68-80th week of treatment he developed castration resistance. Bicalutamide was then discontinued. He chose to begin practicing Falun Gong (FLG) at week 89 as an alternative form of care while continuing two doses of leuprolide acetate. His PSA decreased by 86% within five weeks, he walked independently at 17 weeks and bone metastases disappeared in 41-43 weeks after beginning to practice Falun Gong. He also reported better psychosocial functioning. His treating physician assessed that his prostate malignancy was “clinically, under control” and “his overall functional status is excellent.” The patient survived a total of 263 weeks (61.4 months) post-diagnosis, including 183 weeks (42.3 months) after developing castration resistance.</ns3:p><ns3:p> <ns3:bold>Conclusion:</ns3:bold> This castration-resistant terminal prostate cancer patient gained significant clinical benefits after practicing Falun Gong.</ns3:p>

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.528
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.003
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.096
GPT teacher head0.408
Teacher spread0.312 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes1
Has abstractyes

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