Suspected Infective Endocarditis Finally Turned Out to Be Levamisole-Induced Vasculitis: A Case Report and Review of Literature
Bibliographic record
Abstract
Levamisole is an immune-modulating drug with serious side effects including neutropenia and necrotizing vasculitis. Cocaine is often adulterated with levamisole to potentiate its action. Levamisole-induced vasculitis seen in cocaine users presents diagnostic challenges since it is rare and mimics clinical features of other diseases. It typically presents with a purpuric rash that can involve the nose, ears, cheeks, and extremities. Laboratory findings include leukopenia, lymphocytosis and anti-neutrophil cytoplasmic antibodies (ANCA). No therapies other than supportive care have been found to be effective. Early recognition is critical for supportive therapy and avoidance of potentially harmful therapies like corticosteroids. We report a case of levamisole-induced vasculitis which was suspected to have infective endocarditis at admission. J Med Cases. 2016;7(7):270-273 doi: http://dx.doi.org/10.14740/jmc2538w
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.004 | 0.002 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.002 | 0.002 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.003 | 0.002 |
| Insufficient payload (model declined to judge) | 0.003 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".