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Record W4231291433 · doi:10.1002/9781119676980.ch36

Prenatal and Preimplantation Diagnosis: International Policy Perspectives

2021· other· en· W4231291433 on OpenAlexaffabout
Bartha Maria Knoppers

Bibliographic record

Venuenot available
Typeother
Languageen
FieldMedicine
TopicPrenatal Screening and Diagnostics
Canadian institutionsMcGill University
Fundersnot available
KeywordsSex selectionPreimplantation genetic diagnosisPenetranceChinaOffspringPregnancyGenetic testingPrenatal diagnosisMedicineFamily medicinePolitical scienceEconomic growthDemographyLawObstetricsGeneticsBiologySociologyPhenotypeFetus

Abstract

fetched live from OpenAlex

Diagnostic techniques such as prenatal diagnosis (PND) and preimplantation genetic testing (PGT) provide prospective parents with information on phenotypic or genetic traits, on health status, and on the sex of their offspring. The main goal of both PND and PGT is to avoid having a child with a severe genetic condition. This chapter presents an overview of current laws and policies regarding PND, PGT, and sex selection in 16 different countries: Australia, Belgium, Canada, China, France, India, Israel, Japan, the Netherlands, New Zealand, Singapore, Switzerland, South Africa, Spain, United Kingdom, and the United States. In the countries under study, prenatal diagnosis has long become part of the standard of care in pregnancy. The majority of countries under study govern PND through the adoption of professional guidelines and oversight. PGT is ethically acceptable for conditions that are less serious or of lower penetrance due to the respect for reproductive liberty.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.033
Threshold uncertainty score0.110

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.007
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.004
Science and technology studies0.0030.006
Scholarly communication0.0120.011
Open science0.0020.004
Research integrity0.0130.008
Insufficient payload (model declined to judge)0.0330.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.309
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes2
Has abstractyes

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