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Record W4232884432 · doi:10.32920/ryerson.14655558

Feasibility of Establishing an Enzyme-Linked Immunosorbent Assay (ELISA) Laboratory for the Detection of Dioxins in Economically Marginalized and Developed Countries

2021· preprint· en· W4232884432 on OpenAlexaffabout
Adrienne K. Lee

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldMedicine
TopicSARS-CoV-2 detection and testing
Canadian institutionsMcMaster University
Fundersnot available
KeywordsChristian ministryContaminationSoil testDeveloping countrySample (material)BusinessBiotechnologyEnvironmental scienceWaste managementChemistryEngineeringChromatographyPolitical scienceBiologyEconomic growthEconomicsSoil water

Abstract

fetched live from OpenAlex

Finding a low cost and accessible means of detecting for dioxins in contaminated soil is a necessary step to ensure the health and safety of humans and the environment worldwide. Conventional technologies based on mass spectrometry are expensive and inaccessible. A minimally resourced laboratory and the use of ELISA will be discussed as a feasible, accessible, low cost alternative. The correlation between a minimally resourced laboratory (Ryerson University) and a fully resourced laboratory (Ontario Ministry of the Environment) was strong (n=13, r²=0.888, slope=0.87). To demonstrate the functionality of the minimally resourced laboratory, a supplemental site was characterized using ELISA. Results from the Ryerson and OMOE laboratories produced similar dioxin concentrations of undetectable to 120.26pgTEQg⁻¹ and 32.38 to 163.2pgTEQg⁻¹, respectively. This study illustrates an alternative for evaluating contaminated soil that could serve as a technology transfer for marginalized economies, and provide an accessible form of sample analysis in developed countries.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.009
Threshold uncertainty score0.019

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.069
GPT teacher head0.326
Teacher spread0.256 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2021
Admission routes2
Has abstractyes

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