P398. The costs of care for patients with ulcerative colitis: effect of adalimumab on health care resources utilisation in clinical practice from INSPIRADA
Bibliographic record
Abstract
The clinical outcome was related to clinical (PUCAI score), laboratory (CsA concentration), endoscopic (disease extension and severity), demographic (age, age of onset, and disease duration) data, and previous anti-TNFalpha exposure.Results: Short-term response/remission at day 8 was achieved in 43 out of 59 (81%) and 31 out of 59 (58%) patients, respectively.Long-term remission evaluated 6 months after therapy had been sustained in 19 out of 31 patients (63%).The colectomy rate was 25% (15/59).We observed no significant difference between groups with response/remission vs no response remission at both analysed time points in analysed clinical, laboratory, endoscopic, and demographic data.Previous anti-TNFalpha exposure did not affect clinical outcome.Conclusions: CsA rescue therapy is effective in up to 80% of paediatric UC patients.The 6-months remission was sustained in 32% patient.The colectomy rate was about 25%. P397 Efficacy and safety of sequential rescue therapy with infliximab and tacrolimus in patients with corticosteroid-refractory ulcerative colitis
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.007 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.005 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".