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Record W4233651338 · doi:10.1385/1-59259-300-3:191

Microarray CGH

2003· article· en· W4233651338 on OpenAlexaff
Ben Beheshti, Paul C. Park, Ilan Braude, Jeremy A. Squire

Bibliographic record

VenueMolecular Cytogenetics · 2003
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenomic variations and chromosomal abnormalities
Canadian institutionsUniversity Health NetworkToronto Rehabilitation InstituteUniversity of TorontoOntario Institute for Cancer Research
Fundersnot available
KeywordsComparative genomic hybridizationBiologyCytogeneticsChromosomeMetaphaseOncogeneMolecular cytogeneticsGeneticsCancer researchGeneCell cycle

Abstract

fetched live from OpenAlex

Comparative genomic hybridization (CGH) to metaphase chromosome targets ( 1 , 2 ) has significantly contributed to our understanding of the cancer cytogenetics of more complex malignancies such as solid tumors ( 3 , 4 ). This molecular cytogenetics-based technique (hereafter referred to as “chromosome CGH”) is capable of defining genome-wide DNA copy number imbalances in sample cells relative to a normal reference in a single experiment. Chromosome CGH has greatly increased our understanding of tumor biology and progression since the minimal recurrent regions of chromosomal gain and loss are likely to contain novel oncogene(s) and tumor suppressor gene(s) respectively.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.049
Threshold uncertainty score0.164

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0020.003
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0020.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0490.024

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.211
Teacher spread0.204 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2003
Admission routes1
Has abstractyes

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