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Record W4234695521 · doi:10.1503/cmaj.131676

Dextromethorphan abuse

2014· article· en· W4234695521 on OpenAlexaffvenue
Tony Antoniou, David N. Juurlink

Bibliographic record

VenueCanadian Medical Association Journal · 2014
Typearticle
Languageen
FieldMedicine
TopicRespiratory and Cough-Related Research
Canadian institutionsUniversity of TorontoInstitute for Clinical Evaluative SciencesSunnybrook Health Science CentreSt. Michael's Hospital
Fundersnot available
KeywordsDextromethorphanPhencyclidineKetamineDextrorphanDissociativeMetaboliteIngestionMedicinePharmacologyDrugs of abuseAnesthesiaNMDA receptorReceptorInternal medicineDrug

Abstract

fetched live from OpenAlex

At large doses used recreationally (300 to > 1500 mg), dextromethorphan and its metabolite dextrophan block N -methyl-d-aspartate receptors, producing dissociative effects similar to those of phencyclidine and ketamine.1 Neurobehavioural effects can begin within one hour after ingestion, are dose-

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.004
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.540
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0080.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.281
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations25
Published2014
Admission routes2
Has abstractyes

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