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Record W4235217784 · doi:10.1002/14651858.cd007435

Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension

2008· reference-entry· en· W4235217784 on OpenAlexaff
Meghan Ho, Anthony Bellusci, James M Wright

Bibliographic record

VenueCochrane Database of Systematic Reviews · 2008
Typereference-entry
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCoenzyme Q10 studies and effects
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsCoenzyme Q10Blood pressureMedicineAdverse effectCardiologyPulse pressureInternal medicineHeart ratePharmacology

Abstract

fetched live from OpenAlex

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: Primary objective: To determine the dose‐related effect of coenzyme Q10 on morbidity and mortality in hypertensive patients. To determine the dose‐related effect of coenzyme Q10 on systolic and diastolic blood pressure in hypertensive patients. Secondary objectives: To determine the dose‐related effects of coenzyme Q10 on heart rate and pulse pressure. To determine the effects of coenzyme Q10 in different doses on withdrawals due to adverse effects.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.014
metaresearch head score (Gemma)0.044
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.045
Threshold uncertainty score0.149

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0140.044
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0100.009
Bibliometrics0.0070.007
Science and technology studies0.0010.001
Scholarly communication0.0040.003
Open science0.0020.002
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0450.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.301
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2008
Admission routes1
Has abstractyes

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