Distinct Neurocognitive Profiles in Multiple Sclerosis Subtypes
Bibliographic record
Abstract
An effect size analysis was used to review the neuropsychological literature of multiple sclerosis (MS) to determine whether reliable neurocognitive test deficits and differences between chronic-progressive and relapse-remitting subtypes are apparent. Studies dating back to 1983 were gathered and the neuropsychological test results from a total of 1,845 patients with MS, and 1,265 healthy controls, were synthesized using meta-analytic principles. The results indicate that neurocognitive impairment is indeed evident in patients with MS on a number of cognitive tasks and test variables. Secondly, distinct patterns of neurocognitive deficits are evident in chronic-progressive and relapse-remitting subtypes of MS. Finally, relations between neurocognitive impairment and clinical and demographic attributes of patients with MS were revealed.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.032 | 0.044 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.004 | 0.013 |
| Bibliometrics | 0.007 | 0.004 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".