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Oral Vitamin K for Warfarin-Associated Coagulopathy

2003· article· en· W4236517963 on OpenAlexaffabout
Mark Crowther

Bibliographic record

VenueAnnals of Internal Medicine · 2003
Typearticle
Languageen
FieldNursing
TopicVitamin K Research Studies
Canadian institutionsSt. Joseph's Hospital
Fundersnot available
KeywordsMedicineWarfarinCoagulopathyVitaminVitamin kSurgeryInternal medicineAtrial fibrillation

Abstract

fetched live from OpenAlex

Letters1 April 2003Oral Vitamin K for Warfarin-Associated CoagulopathyMark A. Crowther, MD, MScMark A. Crowther, MD, MScSt. Joseph's Hospital; Hamilton, Ontario L8N 4A6, Canada (Crowther)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-138-7-200304010-00030 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Weideman and Patel raise a number of salient points. We agree that our results apply only to patients who receive the forms of vitamin K that we administered and should be confirmed if other formulations (such as tablets) are to be used. Furthermore, we agree that the relative times from administration of vitamin K to subsequent INR determinations are critical. In our study, these times were available for all but two patients and were very similar (23.5 vs. 23.0 hours in the oral and subcutaneous groups, respectively [P > 0.2]). Finally, although many medications are dosed according to ...Reference1. Crowther MA, Julian J, McCarty D, Douketis J, Kovacs M, Biagoni L, et al. . Treatment of warfarin-associated coagulopathy with oral vitamin K: a randomised controlled trial. Lancet. 2000;356:1551-3. [PMID: 11075768] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Mark A. Crowther, MD, MScAffiliations: St. Joseph's Hospital; Hamilton, Ontario L8N 4A6, Canada (Crowther) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoOral Vitamin K Lowers the International Normalized Ratio More Rapidly Than Subcutaneous Vitamin K in the Treatment of Warfarin-Associated Coagulopathy Mark A. Crowther , James D. Douketis , Terri Schnurr , Luigi Steidl , Valentina Mera , Carolina Ultori , Achille Venco , and Walter Ageno Oral Vitamin K for Warfarin-Associated Coagulopathy Rick Weideman and Amit P. Patel Oral Vitamin K for Warfarin-Associated Coagulopathy Elin Ringstrom and Heather Long Metrics 1 April 2003Volume 138, Issue 7Page: 611KeywordsAlcoholsAtrial fibrillationBody weightCoagulopathyDeep vein thrombosisInternational normalized ratioLiverProphylaxisVitamin K ePublished: 1 April 2003 Issue Published: 1 April 2003 Copyright & PermissionsCopyright © 2003 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.010
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.599
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.010
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.096
GPT teacher head0.407
Teacher spread0.311 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2003
Admission routes2
Has abstractyes

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