Bibliographic record
Abstract
Letters7 April 2015ChikungunyaTariq Al-Araimi, MD and Shikha Mittoo, MD, MHSTariq Al-Araimi, MDFrom University of Toronto and Mount Sinai Hospital and University of Toronto, Toronto, Ontario, Canada.Search for more papers by this author and Shikha Mittoo, MD, MHSFrom University of Toronto and Mount Sinai Hospital and University of Toronto, Toronto, Ontario, Canada.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L15-5076-2 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We read Hamer and Chen's article (1) with great interest. However, chronic chikungunya arthritis can persist for months after infection (2, 3). Among 47 travelers returning from the Indian Ocean islands, including Comoros, Mayotte, Mauritius, the Seychelles, and Réunion Island, followed for 14 months, late (developing after the 10th day) arthropathy—defined by the presence of at least 1 of the following symptoms: symmetric oligo- or polyarthritis accompanied by morning stiffness, nonspecific edema or tenosynovitis, or worsening of mechanical pain in a preexisting injured joint or bone—was identified in 38 persons ( 2). In another series of 21 ...References1. Hamer DH, Chen LH. Chikungunya: establishing a new home in the Western hemisphere. Ann Intern Med. 2014;161:827-8. [PMID: 25244354] doi:10.7326/M14-1958 LinkGoogle Scholar2. Simon F, Parola P, Grandadam M, Fourcade S, Oliver M, Brouqui P, et al. Chikungunya infection: an emerging rheumatism among travelers returned from Indian Ocean islands Report of 47 cases. Medicine (Baltimore). 2007;86:123-37. [PMID: 17505252] CrossrefMedlineGoogle Scholar3. Bouquillard E, Combe B. A report of 21 cases of rheumatoid arthritis following Chikungunya fever A mean follow-up of two years. Joint Bone Spine. 2009;76:654-7. [PMID: 19945329] doi:10.1016/j.jbspin.2009.08.005 CrossrefMedlineGoogle Scholar4. Chopra A, Anuradha V, Lagoo-Joshi V, Kunjir V, Salvi S, Saluja M. Chikungunya virus aches and pains: an emerging challenge. Arthritis Rheum. 2008;58:2921-2. [PMID: 18759351] doi:10.1002/art.23753 CrossrefMedlineGoogle Scholar5. Jaffar-Bandjee MC, Das T, Hoarau JJ, Krejbich Trotot P, Denizot M, Ribera A, et al. Chikungunya virus takes centre stage in virally induced arthritis: possible cellular and molecular mechanisms to pathogenesis. Microbes Infect. 2009;11:1206-18. [PMID: 19835977] doi:10.1016/j.micinf.2009.10.001 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From University of Toronto and Mount Sinai Hospital and University of Toronto, Toronto, Ontario, Canada.Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOf InterestForms.do?msNum=L15-0053. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoChikungunya: Establishing a New Home in the Western Hemisphere Davidson H. Hamer and Lin H. Chen Chikungunya: Establishing a New Home in the Western Hemisphere Davidson H. Hamer and Lin H. Chen Chikungunya William Rodriguez-Cintron Chikungunya Davidson H. Hamer and Lin H. Chen Chikungunya Davidson H. Hamer and Lin H. Chen Chikungunya William Rodriguez-Cintron Metrics Cited ByCaracterización clínica e inmunológica de la artropatía crónica por virus chikungunya y su relación con discapacidad funcional y afectación de la calidad de vida en una cohorte de pacientes colombianosClinical and immunological features of post-chikungunya virus chronic arthritis and its effect on functional ability and quality of life in a cohort of Colombian patients 7 April 2015Volume 162, Issue 7Page: 531-532KeywordsAnalgesicsArthralgiaArthritisChikungunya infectionConnective tissue diseasesDNAMethotrexateRheumatoid arthritisSteroidsStiffness ePublished: 7 April 2015 Issue Published: 7 April 2015 CopyrightCopyright © 2015 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.004 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.002 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.002 | 0.003 |
| Insufficient payload (model declined to judge) | 0.068 | 0.020 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".