MétaCan
Menu
Back to cohort
Record W4238456200 · doi:10.26434/chemrxiv.6957221

Scandium Alkyl and Hydride Complexes Supported by a Pentadentate Diborate Ligand: Reactions with CO2 and N2O

2018· preprint· en· W4238456200 on OpenAlex
Warren E. Piers, Daniel W. Beh, Iker Del Rosal, Laurent Maron, Benjamin S. Gelfand, Chris Gendy, Jianbin Li

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueChemRxiv · 2018
Typepreprint
Languageen
FieldChemistry
TopicOrganoboron and organosilicon chemistry
Canadian institutionsUniversity of Calgary
FundersNatural Sciences and Engineering Research Council of CanadaChinese Academy of SciencesAlexander von Humboldt-Stiftung
KeywordsChemistryDimerHydrideLigand (biochemistry)Medicinal chemistryAlkylStereochemistryMetalOrganic chemistry

Abstract

fetched live from OpenAlex

Alkyl and hydrido scandium complexes of the dianionic pentatdentate ligand B<sub>2</sub>Pz<sub>4</sub>Py are reported. The key starting material (B<sub>2</sub>Pz<sub>4</sub>Py)ScCl is readily prepared and alkylated with organolithium reagents RLi (R = CH<sub>3</sub>, CH<sub>2</sub>SiMe<sub>3</sub>, CH<sub>2</sub>SiMe<sub>2</sub>Ph, CH<sub>2</sub>CH<sub>2</sub>CH<sub>3</sub> and CH<sub>2</sub>CHMe<sub>2</sub>) to form alkyl derivatives in 61-93% yields. These compounds are very thermally stable and do not undergo sigma bond metathesis reactions with dihydrogen. The hydrido complex was prepared from (B<sub>2</sub>Pz<sub>4</sub>Py)ScCl and NaHBEt<sub>3</sub> in 80% yield and was found to be more stable by 28 kcal mol<sup>-1</sup> as a dimer, rather than a monomeric hydrido complex. However, the monomer is accessible through dissociation of the dimer at 80˚C. All of the compounds (B<sub>2</sub>Pz<sub>4</sub>Py)ScR react with water to form the bridging oxo dimer (B<sub>2</sub>Pz<sub>4</sub>Py)ScOSc(B<sub>2</sub>Pz<sub>4</sub>Py). The reactivity of the hydrido and methyl complexes towards carbon dioxide was explored; heating to 80˚C results in the formation of k<sup>2</sup> formato and acetate complexes, respectively. The mechanisms were studied via density function theory and distinct transition states for insertion of CO<sub>2</sub> into the Sc-R (R = H, CH<sub>3</sub>) were found, with the insertion into the Sc-CH<sub>3</sub> being more enthalpically difficult (by 18 kcal mol<sup>-1</sup>) than insertion into Sc-H. The slow rate of reaction between [(B<sub>2</sub>Pz<sub>4</sub>Py)ScH]<sub>2</sub> and CO<sub>2</sub> is attributed to the barrier associated with dimer dissociation. In both insertion reactions, the kinetic products are k<sup>1</sup> formato or acetate complexes that are only slightly less stable than the observed k<sup>2</sup> derivatives. The k<sup>1</sup> compounds can therefore be trapped by treating the k<sup>2</sup> isomers with <i>tris</i>-pentafluorophenyl borane.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.038
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.241
Teacher spread0.229 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it