Laser Synthesis of Nanostructured Glass for Selective Cell Proliferation or Apoptosis
Bibliographic record
Abstract
The state-of-the-art in synthesis of nanostructured cell and contra-cell surfaces relies on techniques that utilize elaborate precursor chemicals, catalysts, or vacuum conditions, and any combination thereof. Two types of nanostructures, Na2O nanotips and SiO2 nanofibers, have been fabricated on soda-lime glass using ultrafast laser ablation. Control over nanotip width was demonstrated via laser dwell time and a new tip formation mechanism is proposed. The nanofibers generated in this work display a level of nanomorphology unseen in other fiber fabrication methods. The resulting fibers show striking morphological similarity to proteins that comprise the natural extra cellular matrix. The interaction of both nanostructures with NIH 3T3 fibroblasts was explored by incubating nanostructured glass with fibroblasts over periods of 12 hours, 1 day, or 1 week. Nanotip structures appeared to induce apoptosis in cells while nanofibers influenced cells to display unique, healthy characteristics such as preferential adhesion to nanofibers and increased microvilli generation.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".