Moderated Poster Session III: Stones/Endourology, Laparoscopy/Robotics
Bibliographic record
Abstract
Background: Previous studies investigating urinary stone risk after colon surgery have demonstrated significant reductions in urinary pH, volume, citrate, and magnesium that correspond to an increased incidence of kidney stones.These studies, however, have consistently included patients with inflammatory bowel disease (IBD) which may bias their findings due to known urinary abnormalities present prior to surgery and differences in length of bowel removed compared to other types of colon surgery.This study aims to evaluate urinary stone risk after colon surgery in patients with and without IBD.Methods: Retrospectively, baseline 24-hour urine samples of 21 kidney stone patients with a history of colon resections were evaluated from a data set of over 800 patients.Urinary chemistries of those who required colon surgery for IBD (9 patients) and non-IBD reasons (12 patients) were compared to each other and a control of 52 first-time stone formers without bowel disease.Results: The IBD colectomy group had a significantly lower urinary pH (5.55 vs. 6.08,p=0.003), magnesium (41.8 mg/d vs. 103.7 mg/d, p=0.0002), citrate (109.8 mg/d vs. 230.4mg/d, p=0.0001), sodium (95.2 mmol/d vs. 7.9 mmol/d, p=0.013), and calcium (109.8 mg/d vs. 230 mg/d, p=0.01) than the control.The non-IBD colectomy group had lower pH (5.69 vs. 6.09,p=0.015) and higher supersaturation of uric acid (1.62 vs. 0.87, p=0.015) compared to the control.The IBD colectomy group revealed a lower magnesium (p=0.04),citrate (p=0.007), and sodium (p=0.045)than the non-IBD colectomy group.66% of the colectomies in the IBD group were total while 100% of the colectomies in the non-IBD group were partial.Conclusions: The urinary stone risk of colectomy patients with IBD is significantly different from colectomy patients without IBD and is more reflective of abnormalities present in IBD patients prior to surgery such as low citrate, magnesium, and urinary pH.It is likely the IBD patients biased the findings of previous studies investigating the urinary stone risk after colon surgery.Patients who underwent colon surgery for non-IBD reasons, however, have few urinary abnormalities and a urinary risk more similar to first-time stone formers.The difference in urinary risk of colectomy patients with and without IBD may be explained by the intrinsic stone risk present in IBD and the differences in length of bowel removed. P29
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.002 |
| Meta-epidemiology (narrow) | 0.002 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.002 | 0.000 |
| Scholarly communication | 0.002 | 0.001 |
| Open science | 0.001 | 0.003 |
| Research integrity | 0.003 | 0.002 |
| Insufficient payload (model declined to judge) | 0.426 | 0.178 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".