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Record W4239968306 · doi:10.1007/978-1-60761-219-3_36

Chelation and Heart Disease

2011· book-chapter· en· W4239968306 on OpenAlexaff

Bibliographic record

VenueHumana Press eBooks · 2011
Typebook-chapter
Languageen
FieldMedicine
TopicGallbladder and Bile Duct Disorders
Canadian institutionsOttawa HospitalUniversity of Ottawa
Fundersnot available
KeywordsChelationChelation therapyMedicineInternal medicineChemistryInorganic chemistry

Abstract

fetched live from OpenAlex

Obstruction of coronary arteries by atheromatous plaques (accumulation of lipids, calcium deposition, and fibrotic tissue) followed by accumulation of platelets, and finally thrombosis are the causes of most heart attacks and sudden death ( Atherosclerosis/Atheroma ). Chelation, by administering intravenous ethylenediamine tetraacetic acid (EDTA), is a method for clearing atheromatous obstruction of coronary arteries, which is analogous to using Drano to clean obstructed pipes. The treatment costs approximately $4,000 per year, and surprisingly during the 1980s and 1990s, more than half a million patients underwent it in the USA annually. It appears that in Canada, approximately 8% of patients undergoing coronary angiography have tried chelation therapy during the 90s. Controversies have raged in the past 40 years regarding the value of chelation therapy. It is crucial for the public to learn that effective therapy is now available (statins to reduce low density...

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.035
Threshold uncertainty score0.118

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0350.016

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.071
GPT teacher head0.268
Teacher spread0.196 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2011
Admission routes1
Has abstractno

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