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Record W4240339401 · doi:10.1002/047084289x.rn02074

Trifluoroethylamine

2017· reference-entry· en· W4240339401 on OpenAlexaff
Nicolas Diercxsens

Bibliographic record

VenueEncyclopedia of Reagents for Organic Synthesis · 2017
Typereference-entry
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicFluorine in Organic Chemistry
Canadian institutionsUniversité de Montréal
Fundersnot available
KeywordsChemistryReductive aminationAmine gas treatingSolubilityExtraction (chemistry)SolventSalt (chemistry)DiazoLiquid ammoniaOrganic chemistryChromatographyAmmonia

Abstract

fetched live from OpenAlex

[753-90-2] C2H4F3N (MW 99.06) InChI = InChI=1S/C2H4F3N/c3-2(4,5)1-6/h1,6H2 InChIKey = KIPSRYDSZQRPEA-UHFFFAOYSA-N (amine building block, amide synthesis, diazo precursor, reductive amination, sulfonamide precursor) Alternate Names: 2-amino-1,1,1-trifluoroethane; 2,2,2-trifluoroethanamine. Physical Data: bp 36–37 °C, d = 1.262 g cm−3. Solubility: common organic solvents (the HCl salt is soluble in water). Form Supplied in: liquid (may be slightly yellow). Handling, Storage, and Precautions: highly flammable liquid and vapors. Toxic by inhalation, manipulate under a fume hood. Wear protective gloves, clothing, and eyewear. Store at 2–8 °C. Purification: the amine is usually sold as its HCl salt. The free amine can be recovered after a basic wash and extraction into an organic solvent. Distillation is an alternative purification procedure.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.121
Threshold uncertainty score0.404

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0000.001
Open science0.0020.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.1210.094

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.088
GPT teacher head0.401
Teacher spread0.313 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2017
Admission routes1
Has abstractyes

Explore more

Same venueEncyclopedia of Reagents for Organic SynthesisSame topicFluorine in Organic ChemistryFrench-language works237,207